It had been observed that some cystic nodules change morphologically with ultrasonographic (US) features suspicious for malignancy. The aim of this study was to evaluate the US characteristics of benign cystic nodules mimicking papillary thyroid carcinoma (PTC) during interval changes. Between January 2009 and October 2009, 26 patients with benign cystic nodules showing marked hypoechogenicity ...

BACKGROUND New biomarkers are needed to detect pleural mesothelioma at an earlier stage and to individualize treatment strategies. We investigated whether fibulin-3 in plasma and pleural effusions could meet sensitivity and specificity criteria for a robust biomarker. METHODS We measured fibulin-3 levels in plasma (from 92 patients with mesothelioma, 136 asbestos-exposed persons without cance...

A case of benign mesothelioma of the epididymis, successfully treated with local resection, is reported. Conservative surgery is allowed when malignancy is excluded by frozen section.

Benign multicystic peritoneal mesothelioma: a rare tumor of the abdomen, is a diagnostic dilemma. This report emphasizes the importance of diagnostic laparoscopy in the diagnosis of the tumour.

Background: Ovarian cancer is the fifth most common cancer in woman and the fifth most frequent cause of cancer death. Ovarian cancers are usually asymptomatic until metastasized, patients have advanced disease at diagnosis in more than 2/3 of the cases. Totally 75-80 % of ovarian masses are benign. The strongest patient related risk factor for ovarian cancer is increasing age. The most ovarian...

BACKGROUND CT plays a valuable role in assessment of patients with a wide variety of diseases of the pleura, and pulmonologists should be aware of the significance of different CT findings for the differential diagnosis of benign and malignant pleural diseases. METHODS 155 patients with pleural disease who had undergone CT scans of the lungs and thorax before treatment were enrolled. We retro...

Primary malignant fibrous histiocytoma (MFH) is a rare and biologically aggressive tumor. Differential diagnosis must include cystic neoplasms of the pancreas (mucinous and serous cystoadenoma or cystocarcinoma), cystic lymphangioma or mesothelioma and retroperitoneal haematoma. Making the right diagnosis preoperatively may be often difficult, but MFH may be suspected when a huge retroperitonea...

A panel of seven monoclonal antiepithelial antibodies of different specificities, including anticytokeratin, human milk fat globule membrane, Ca, and carcinoembryonic antigen (CEA) were used with the alkaline phosphatase-antialkaline phosphatase (APAAP) immunostaining technique to determine their value in the differentiation between benign and malignant mesothelial cells and lung carcinoma in h...

A panel of seven monoclonal antiepithelial antibodies of different specificities, including anticytokeratin, human milk fat globule membrane, C, and carcinoembryonic antigen (CEA) were used with the alkaline phosphatase-antialkaline phosphatase (APAAP) immunostaining technique to determine their value in the differentiation between benign and malignant mesothelial cells and lung carcinoma in hi...

Introduction There are a variety of predictable circumstances in which benign lung lesions are at risk of being interpreted as malignant neoplastic processes. This brief overview will focus on three of them chosen because of their relative frequency in cases received for consultation. The most common diagnostic challenge is separating hyperplasia and/or metaplasia of non-neoplastic respiratory ...