BACKGROUND Bleeding symptoms commonly seen by multiple physician specialties may belie undiagnosed congenital or acquired bleeding disorders. Acquired hemophilia is a potentially life-threatening cause of unexplained acute bleeding manifested by an abnormal activated partial thromboplastin time (aPTT) that does not correct with 1:1 mixing with normal plasma. METHODS Practicing physicians (hem...

HST provides an unparalleled venue for high contrast imaging which has enabled new observational domains in exoplanet and debris disk imaging. Unburdened by atmospheric "seeing", NICMOS and STIS achieve very low levels of background contamination from the wings of stellar point spread functions (PSF). Coronagraphy provides additional contrast gains approaching an order of magnitude at small ang...

The Type Ic supernovae are probably “nearly-nude” core collapse events. They are thus of special interest in terms of their evolutionary origin, but also as the source of potential clues to the explosion process that may not be obtained from other supernovae. Study of Type Ic shows that they are distinct from Type Ia, even those of the dimmer, redder variety. Type Ic also suggest that the histo...

32 The entorhinal cortex (ERC) is critically implicated in temporal lobe epileptogenesis – 33 the most common type of adult-epilepsy. Previous studies have suggested that epileptiform 34 discharges likely initiate in seizure-sensitive deep-layers (V-VI) of the medial entorhinal area 35 (MEA) and propagate into seizure-resistant superficial-layers (II-III) and hippocampus, 36 establishing a lami...

The beginning student of histology is frequently confused by the increasing burden of detail that is incorporated into the more encyclopedic texts. For such students the more condensed treatment available in this book will prove useful since it provides, in skeleton form, the essentials of the subject. In this sense the present (third) edition of this work fills a real need in providing the stu...

Closely related species of Drosophila tend to have similar genome sizes. The strong imbalance in favor of small deletions relative to insertions implies that the unconstrained DNA in Drosophila is unlikely to be passively inherited from even closely related ancestors, and yet most DNA in Drosophila genomes is intergenic and potentially unconstrained. In an attempt to investigate the maintenance...

The beginning student of histology is frequently confused by the increasing burden of detail that is incorporated into the more encyclopedic texts. For such students the more condensed treatment available in this book will prove useful since it provides, in skeleton form, the essentials of the subject. In this sense the present (third) edition of this work fills a real need in providing the stu...

The size of this monograph and its moderate price belie the wealth of information contained within its pages. This book is a competent attempt to assemble biochemical and physiological data and correlate these findings with ultrastructure of the rat anterior pituitary. There are twelve chapters. The first two are devoted to definitions and experimental procedures. The next six chapters center a...

The entorhinal cortex (ERC) is critically implicated in temporal lobe epileptogenesis--the most common type of adult epilepsy. Previous studies have suggested that epileptiform discharges likely initiate in seizure-sensitive deep layers (V-VI) of the medial entorhinal area (MEA) and propagate into seizure-resistant superficial layers (II-III) and hippocampus, establishing a lamina-specific dist...

Geoscientists are trained to represent multi-component datasets by projecting onto relatively simple diagrams on two-dimensional surfaces. These projections are used to represent a variety of phenomena ranging from spatial relations to physico-chemical processes. By using projections, it is possible to create simple diagrams as models or analogs of complex and heterogeneous natural systems usin...