Phospholipase A(2) (PLA(2)), a regulatory enzyme found in most mammalian cells, catalyzes the breakdown of membrane phospholipids to arachidonic acid. There are two major cytosolic types of the enzyme, calcium-dependent (cPLA(2)) and calcium-independent (iPLA(2)) PLA(2). The present study investigated whether or not iPLA(2) plays a role in the endothelium-dependent contractions of the aorta of ...

Biological networks are important for biologists to represent and understand biological systems. These networks can be represented by languages such as BEL and SBML. Automatically extracting these descriptions and representing them in the biological system languages can improve the efficiency of constructing these networks. In this paper, we expand our previous Named Entity Recognition and Norm...

PURPOSE To test the ability of two preparations of FGF2-saporin, either FGF2 chemically conjugated to saporin (FGF2-SAP) or genetically engineered FGF2-saporin (rFGF2-SAP) to inhibit the growth of bovine epithelial lens (BEL) cells in vitro when in solution and when immobilized on heparin surface-modified (HSM) polymethylmethacrylate (PMMA) intraocular lenses (IOLs). METHOD Bovine epithelial ...

Amaç: Bu araştırmanın amacı, taekwondo sporcularında core egzersizlerin antropometrik özellikler ve bazı performans parametrelerine etkisini incelemektir. Gereç Yöntemler: Araştırmanın katılımcılarını 30 genç erkek taekwando sporcusu oluşturmuştur. Araştırma grubundaki taekwandocular dinamik egzersiz (DCE) yapanlar (n=10), statik (SCE) (n=10) kontrol grubu olmak üzere 3 gruba ayrılmıştır. Dinam...

AIM To study the effects of Pinus massoniana bark extract (PMBE) on cell proliferation and apoptosis of human hepatoma BEL-7402 cells and to elucidate its molecular mechanism. METHODS BEL-7402 cells were incubated with various concentrations (20-200 microg/mL) of PMBE for different periods of time. After 48 h, cell proliferation was determined by 3-(4,5-dimethyl-thiazolyl-2)-2,5-diphenyl tetr...

Zebrafish mutant belladonna (bel) carries a mutation in the lhx2 gene (encoding a Lim domain homeobox transcription factor) that results in a defect in retinotectal axon pathfinding, which can lead to uncrossed optic nerves failing to form an optic chiasm. Here, we report on a novel swimming behavior of the bel mutants, best described as looping. Together with two previously reported oculomotor...

The helicases human DDX3 and Drosophila Belle (Bel) are part of a well-defined subfamily of the DEAD-box helicases. Individual subfamily-members perform a myriad of functions in nuclear and cytosolic RNA metabolism. It has also been reported that DDX3X is involved in cell signaling, including IFN-α and IFN-β inducing pathways upon viral infection as well as in Wnt signaling. Here we used a coll...