overlap syndrome, which is known as the coexistence of chronic obstructive pulmonary disease (copd) and obstructive sleep apnea (osa), was first defined by flenley. although it can refer to concomitant occurrence of any of the pulmonary diseases and osa, overlap syndrome is commonly considered as the coexistence of osa and copd. this disease has unique adverse health consequences distinct from ...

Down syndrome is one of the most common causes of mental retardation observed in approximately 1/700 live birth. The use of two or more STR markers related to chromosome 21 facilitates the diagnosis of Down syndrome within about six hours from the collection of the samples. This is the first study has been performed in Iranian population to assess the diagnostic value of using small tandem repe...

conclusions in our study, portal venous thrombosis was detected in the patient who died during the acute period only. a study including large numbers of budd-chiari-syndrome patients with behcet’s disease and portal venous thrombosis would be helpful to determine the prognostic significance of portal venous thrombosis in budd-chiari-syndrome patients with behcet’s disease. in addition, patients...

Dear Editor, We thank Vercelli et al.1 for their comments on our paper: Why do emergency department clinicians miss acute aortic syndrome? A case series and descriptive analysis. fully agree with the authors, that investigating heart aorta using POCUS may allow an earlier diagnosis therefore more expedient treatment of a patient syndrome (AAS). would also authors is point care test good specifi...

Metabolic syndrome is highly prevalent in type 2 diabetics and is a strong risk factor for cardiovascular diseases in such patients. The aim of this study was to determine the prevalence of metabolic syndrome according to the three criteria of ATPIII, IDF and the new criteria for metabolic syndrome diagnosis in Kerman, Iran.This cross-sectional study was performed on 950 diabetic type 2 patient...

Klinefelter syndrome is characterised by advancing testicular function deterioration causing aspermatogenesis and androgen deficiency. Klinefelter patients characteristically have complete male sex differentiation, and genital anomalies are infrequently associated. Penoscrotal malformations at birth are very rare in this syndrome. Nonetheless, it is important to know the association, as one of...

background: the treatment of acute promyelocy!c leukemia with all-trans-re!noic acid (atra) some!mes results in a syndrome characterized by fever, respiratory distress, weight gain, pleural or pericardial effusion, and pulmonary infiltrates. we report the major clinical and radiologic features of atra syndrome. materials and methods: in the past, occasional case reports and literature pertainin...

introduction turner syndrome is the most common chromosomal abnormality in females. girls with turner syndrome have an abmormal or missing x choromosme that causes short stature, ovarian failure, renovascular and cardiac anomalies. it has been shown that there is a tendency to obesity in the turner syndrome. this prospective study has been done to evaluate whether body mass index (bmi) is diffe...

The article presents a clinical case of rare autoinflammatory disease – family Muckle Wells syndrome. diversity manifestations and the impossibility confirming diagnosis without genetic study by DNA sequencing determine complexity delay in diagnosis. development severe complications and, as consequence, fatal outcome necessitates early described demonstrates importance for timely disease, featu...