The degeneration of articular cartilage represents an ongoing challenge at the clinical and basic level. Tissue engineering and regenerative medicine using stem/progenitor cells have emerged as valid alternatives to classical reparative techniques. This review offers a brief introduction and overview of the field, highlighting a number of tissue sources for stem/progenitor cell populations. Emp...

A ribosomal protein, showing no homology with other known prokaryotic ribosomal proteins, was isolated and characterized from the thermophilic eubacteria, Thermus thermophilus, T. aquaticus and T. flavus. This small (26 amino acids) and strongly basic (1 acidic and 13 basic residues) protein displayed the same primary structure from all three sources. Interestingly, it shows about 65% homology ...

This paper describes SPMED, a system for robust and accurate linguistic parsing of medical documents which is used in several industrial products. The basic design criterion of the system is of providing a set of basic powerful, robust, and generic linguistic knowledge sources and modules which can easily customized for processing different tasks in a flexible manner. The main application is se...

BACKGROUND The role of basic science knowledge in clinical diagnosis is unclear. There has been no experimental demonstration of its value in helping students recall and organize clinical information. This study examines how causal knowledge may lead to better recall and diagnostic skill over time. METHOD Undergraduate medical students learned either four neurological or rheumatic disorders. ...

A widespread assumption in theories of emotion is that there exists a small set of basic emotions. From a biological perspective, this idea is manifested in the belief that there might be neurophysiological and anatomical substrates corresponding to the basic emotions. From a psychological perspective, basic emotions are often held to be the primitive building blocks of other, nonbasic emotions...

Research and theory concerning the nature and sources of well-being has been undertaken through varied approaches. Two such approaches are the capability approach and self-determination theory (SDT), both of which have postulated specific factors deemed necessary for human well-being and flourishing. In two studies we examine the relations between capabilities and well-being indicators, as well...

In this paper, a beamforming correction for identifying dipole sources by means of phased microphone array measurements is presented and implemented numerically and experimentally. Conventional beamforming techniques, which are developed for monopole sources, can lead to significant errors when applied to reconstruct dipole sources. A previous correction technique to microphone signals is exten...