Genome-wide association studies and physiological investigations have linked alterations in acid-base transporters to hypertension. Accordingly, Na(+)-coupled HCO(-) 3-transporters, Na(+)/H(+)-exchangers, and anion-exchangers have emerged as putative mechanistic components in blood pressure disturbances. Even though hypertension has been studied extensively over the last several decades, the ca...

Circles of Care grantees were provided the opportunity to develop a locally relevant definition of serious emotional disturbance that would be used to define what type of emotional, behavioral, and mental disability would be required to receive services. After conducting detailed assessments of the definition in the guidance for applicants GFA and the definitions used by others in their respect...

This study examines the postural activity of partially constrained subjects for three different initial standing postures in response to disturbances in the sagittal plane. When the ankle strategy suffices for disturbance rejection in response to anterior disturbances, a mostly linear relationship between the ankle torque and ankle angle was observed, resulting in a constant stiffness at the an...

INTRODUCTION It has long been known that changes in the hydrogen ion concentration ([H+]) and carbon dioxide tension (Pco2) of the blood affect respiration. These alterations in ventilation are probably produced by a chemical stimulus at more than one site (Lambertsen et al., 1961). The presence of arterial chemoreceptors in relation to the carotid sinus and aortic arch is well known. Recently,...

Scanning probe imaging is often limited by disturbances, or mechanical noise, from the environment that couple into the microscope. We demonstrate, on a modified commercial atomic force microscope, that adding an interferometer as a secondary sensor to measure the separation between the base of the cantilever and the sample during conventional feedback scanning can result in real-time images wi...

Sepsis-associated encephalopathy (SAE) is a poorly understood and underdiagnosed neurological complication of sepsis. Several conditions commonly associated with sepsis (hepatic or renal dysfunction, electrolyte abnormalities, acid-base disturbances, glycemia disturbances, hypotension, hypoxemia, sedation, body temperature disturbances, and neuroendocrine dysfunction) make SAE evaluation diffic...

We present an investigation of instability during electrophoretic transport of ions in a class of electrolytes called oscillating electrolytes. We analyze the onset of instability in electrophoretic transport in a binary electrolyte by modeling growth of small concentration disturbances over a base state with uniform acid and base concentrations. Our linear stability analysis shows that the gro...

Stewart in 1983 (Can J Physiol Pharmacol 1983: 61: 1444) reintroduced plasma buffer base under the name "strong ion difference" (SID). Buffer base was originally introduced by Singer and Hastings in 1948 (Medicine (Baltimore) 1948: 27: 223). Plasma buffer base, which is practically equal to the sum of bicarbonate and albuminate anions, may be increased due to an excess of base or due to an incr...

In individuals without diabetes, highintensity exercise (HIE) training may reduce (1) the characteristic postexercise rise in plasma glucose with HIE (2–4) and reduces (5,6) the marked acid-base balance perturbations (5–8). In type 1 diabetes, continuous HIE induces sustained hyperglycemia (9,10), while very brief intermittent HIE may reduce hyperglycemia (11). Acid-base disturbances during exe...