Rate of metabolism and temperature regulation were studied in 16 species of South Pacific pigeons, which constitute 13 fruit-eaters, 1 seed-eater, 1 fruit/nut-eater, and 1 fruit/leaf-eater; 14 tropical and two temperate species; and ten mainland and six intermediate- or small-island species. The data presented here and those from 11 additional columbids indicate in an analysis of covariance tha...

Mohanram, M., and Kumar, A. (1975). Archives of Disease in Childhood, 50, 235. Ascorbic acid and tyrosine metabolism in preterm and small-fordates infants. Ascorbic acid levels in plasma and leucocytes and urinary excretion of tyrosyl derivatives (TD) were determined in 11 normal, 18 preterm, and 4 smallfor-dates infants. Concentrations of ascorbic acid in both plasma and leucocytes were found ...

Basal as well as xenobiotic-induced expression of the main enzymes from phase I and phase II of drug metabolism is confined to the perivenous areas of the mammalian liver lobule. Whereas signal transduction pathways that govern xenobiotic-induced expression of these enzymes via ligand-activated transcription factors such as constitutive androstane receptor (CAR) or the aryl hydrocarbon receptor...

Clinical applications of PET studies for dementia are reviewed in this paper. At the mild and moderate stages of Alzheimer's disease (AD), glucose metabolism is reduced not only in the parietotemporal region but also in the posterior cingulate and precuneus. At the advanced stage of AD, there is also a metabolic reduction in the frontal region. In AD patients, glucose metabolism is relatively p...

Eicosapentaenoic acid (EPA), one of the n-3 polyunsaturated fatty acids, has been shown to stimulate leptin mRNA expression and secretion in 3T3-L1 cells. However, other studies have reported inhibitory effects of EPA on leptin expression and secretion in vivo and in vitro. To determine the direct effects of EPA on basal and insulin-stimulated leptin secretion, isolated rat adipocytes were incu...

Lack of insulin results in a catabolic state in subjects with insulin-dependent diabetes mellitus which is reversed by insulin treatment. Amino acid supply, especially branched chain amino acids such as leucine, enhances protein synthesis in both animal and human studies. This small study was undertaken to assess the acute effect of supplemental leucine on protein metabolism in adolescents with...

OBJECTIVES The laboratory mouse is presently the most common model for examining mechanisms of human physiology and disease. Housing temperatures can have a large impact on the outcome of such experiments and on their translatability to the human situation. Humans usually create for themselves a thermoneutral environment without cold stress, while laboratory mice under standard conditions (≈20°...

INTRODUCTION We assessed the correlation between iron deposition and the change of gliocyte metabolism in healthy subjects' basal ganglia region, by using 3D-enhanced susceptibility weighted angiography (ESWAN) and proton magnetic resonance spectroscopy ((1)H-MRS). MATERIAL AND METHODS Seventy-seven healthy volunteers (39 female and 38 male subjects; age range: 24-82 years old) were enrolled ...