This paper presents a methodology for quantitative risk analysis on oil and gas production platforms that incorporates both technical and operational conditions. The basic building blocks of the methodology are barrier block diagrams, event trees, fault trees, and influence diagrams. Barrier block diagrams are used to illustrate the event scenarios and the effect of barrier systems on the scena...

BACKGROUND To identify barriers to participation in a primary oral health care programme aimed at preventing early childhood caries, as perceived by nurses. METHODS Of a total of 140 randomly selected nurses employed in 40 government health centres in Lima, 123 completed a pre-tested questionnaire. Background variables were districts' 'socio-economic status' (SES) and 'years of experience'. F...

This paper takes a fresh look at alternative perspectives on major accident causation theories to highlight the fact that these perspectives can supplement and improve the energy barrier perspective. The paper starts from a literature study of energy barrier perspective, Man-Made Disaster theory (MMD), Conflicting Objective Perspective (COP), Normal Accident Theory (NAT), High Reliability Organ...

Gliomas, particularly glioblastoma multiforme, perturb the bloodbrain barrier and cause brain edema that contributes to morbidity and mortality. The mechanisms underlying this vasogenic edema are poorly understood. We examined the effects of cocultured primary cultured human glioblastoma cells and glioma-derived growth factors on the endothelial cell tight junction proteins claudin 1, claudin 5...

Circulating factors in preeclamptic women are thought to cause endothelial dysfunction and thereby contribute to the progression of this hypertensive condition. Despite the involvement of neurological complications in preeclampsia, there is a paucity of data regarding the effect of circulating factors on cerebrovascular function. Using a rat model of pregnancy, we investigated blood-brain barri...

a method is described by which it is possible to determine the high barrier to ring inversion and hindered rotation by neat racemization of optically active compounds when the racemization is caused by ring inversion or hindered rotation. the method is based preparation of sufficiently pure enantiomers, mainly by chromatography on swollen microcrystalline triacetylcellulose (tac). by this techn...

The stratum corneum (SC), the outermost barrier of mammalian bodies, consists of layers of cornified keratinocytes with intercellular spaces sealed with lipids. The insolubility of the SC has hampered in-depth analysis, and the SC has been considered a homogeneous barrier. Here, we applied time-of-flight secondary ion mass spectrometry to demonstrate that the SC consists of three layers with di...

In this paper, the effects of horizontal stress and dimensions of barrier pillars on the stability of drifts hr been investigated. An elastoplastic hybrid finite/boundary element program has been used. A plastic analysis of stresses in barrier pillars above the drifts in one of the underground coal mines with inclined seams is examined. Computed stresses and safety factor controur lines around ...

Background Despite successful cloning of many mammalian species, the cloning efficiency is extremely low compared to that of IVF raising the possibility of the existence of epigenetic barrier preventing successful cloning. MaterialsAndMethods Using comparative transcriptome analysis comparing transcriptomes of IVF and SCNT embryos and that of donor cells, we identified epigenetic barrier and fi...

Gliomas, particularly glioblastoma multiforme, perturb the blood-brain barrier and cause brain edema that contributes to morbidity and mortality. The mechanisms underlying this vasogenic edema are poorly understood. We examined the effects of cocultured primary cultured human glioblastoma cells and glioma-derived growth factors on the endothelial cell tight junction proteins claudin 1, claudin ...