The b-barrel membrane protein is found in the outer membranes of bacteria, mitochondria and chloroplasts. Approximately 2–3% of the genes in Gram-negative bacterial genomes encode b-barrels. Whereas there are fewer than 20 known three-dimensional b-barrel structures, genomic databases currently contain thousands of b-barrels belonging to dozens of families. New research is revealing the variety...

Membrane proteins, which constitute approximately 20% of most genomes, form two main classes: alpha helical and beta barrel transmembrane proteins. Using methods based on Bayesian Networks, a powerful approach for statistical inference, we have sought to address beta-barrel topology prediction. The beta-barrel topology predictor reports individual strand accuracies of 88.6%. The method outlined...

In the present study, the effect of NBM lesion on the temporal characteristics of response integration evoked by multiple whisker stimulations in the barrel cortex of rats was studied. Nucleus basalis of Meynert (NBM) projects to widespread areas of the cortex and provides the major cholinergic input (80%) to the cerebral cortex. In this study we examined the effects of NBM lesion on the respon...

Rats were raised with altered tactile experience from P0 by removing all but one vibrissa (D1) from one side of the face (D1-spared animals). This procedure (univibrissa rearing) has previously been shown to cause neurons in cortical barrels surrounding D1 to develop greater than normal responses to D1 vibrissa stimulation and smaller than normal responses to principal vibrissa stimulation (Fox...

This work presents a simulation approach to the design and economic evaluation of fuel oil hydrotreating processes for the control of SO2 and NOx emission in an Iranian steam power plant. The percent of fuel oil desulphurization was estimated from the SO2 emissions standards for power plants. Based on two different scenarios according to (I) European and (II) Iranian standards, the design and s...

Abstract As an additional part of the artillery barrel, thermal sleeve is a cladding made insulation or conductive material mounted on outer surface which can greatly reduce bending deformation caused by sunlight exposure thus improving shooting accuracy artillery. In this paper, new type diamond barrel protection efficiency tested and analyzed, after testing, be as high 71.6%, much higher than...

Push-pull cannulae have been extensively employed for the in vivo perfusion of discrete brain regions and investigation of perfusate contents (Gaddum, 1961; Szerb, 1967; Yaksh and Yamamura, 1974; Errington et al., 1983). We wish to report a highly simplified and quick technique for the construction of push-pull cannulae. The outer barrel of the cannula consists of 24-gauge stainless-steel tubin...

FP HP Nose Barrel Fig 1.Visualization of soma – totopic maps in the rat S1 cortex. S1 subdivisions of forepaw (FP, yellow), hindpaw (HP, green), barrel (Barrel, purple), and nose (Nose, red) are represented in 2D coronal t-maps (A) and 3D contour (B), which is in an excellent agreement with the somatotopic maps established by electrophysiology (inset) [4]. Functional MRI of Somatosensory Cortic...