background: ritalin (methylphenidate methylphenidate) is an amphetamine used to treat adhd, symptoms of narcolepsy, and some people with depression. this study was to investigate the effect of ritalin food on blood albumin and some liver enzymes. materials and methods: in this study, 40 male wistar rats were randomized into 4 groups (1 control group, and three experimental groups). in the contr...

introduction: the brain glutamate neurotransmitter system and its nmda receptors in the nucleus accumbens play an important role in the incidence of the phenomena of sensitivity and addiction. the present study examined the inhibitory effect of glutamate nmda receptors in the nucleus accumbens in response to chronic stress. methods: after the unilateral and bilateral cannula placement in the nu...

background: one of the most major obstacles of ovarian tissue vitrification is suboptimal developmental competence of follicles. matrix metalloproteinases 2 (mmp-2) and 9 (mmp-9) and their tissue inhibitors timp-1 and timp-2 are involved in the remodeling of the extracellular matrix in the ovaries. objective: this study aimed to evaluate the expression of mmp-2, mmp-9, timp-1, and timp-2 genes ...

background: preparation of oocytes is one of the critical factors that determine the developmental competence of embryos produced by in vitro fertilization (ivf). objective: in this study, the effect of cysteamine, type of media and glutathione (gsh) level on blastocysts development after in vitro maturation of mouse oocytes were investigated. materials and methods: premature female mice were p...

objective(s): the adverse effects of pyridaben on reproductive system in male animals are not well established. this study was designed to elucidate how pyridaben can effects the histomorphometric, hormonal alternations and reproductive functions of balb/c mice .   materials and methods : for this study, 80 adult and apparently healthy male balb/c mice were divided into three groups viz, contro...

the goal of this study was to investigate the common clinical chemistry and distribution of xanthine oxidase (xo) in selected tissues of a mouse model of menopause. twenty four nmri female mice were divided into three groups: normal control (nc), and ovariectomized (ovx) groups and an estrogen-treated ovariectomized (ovx+e) group which received subcutaneous injection of estradiol benzoate (2 mg...

mice are ideal models for icsi experiments because of the ease of culturing eggs/embryos in vitro and the availability of ample genetic information. unfortunately, it has been extremely difficult. in this study we improved the mouse icsi method by using a new holding pipette that was made of two pipettes such that one pipette was pulled and heat merged into the other one. the outer pipette had ...

neospora caninum (n. caninum) is an apicomplexan parasite and causes abortion and congenital neosporosis in cattle worldwide. in this study, we evaluate the virulence of a n. caninum isolate on mouse strain c57bl/6. six groups of five mice c57bl/6 were intraperitoneally inoculated with 1 × l07, 1.5 × l07, 2 × l07, 3 × l07 and 4 × l07 tachyzoites and a control inoculum of dmem, respectively. cli...

objective: this study presents an efficient, cost-effective method to improve proliferation and colonization of spermatogonial stem cells (sscs) in vitro. methods: isolated sscs from neonate mice were cultured in dmem culture medium with 10% fetal bovine serum (fbs). in the first phase of the study, the temperature was controlled by low intensity pulsed ultrasound stimulation (lipus) of the pla...