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تعداد نتایج: 98 فیلتر نتایج به سال:
This work investigates X-PACT (X-ray Psoralen Activated Cancer Therapy): a new approach for the treatment of solid cancer. X-PACT utilizes psoralen, a potent anti-cancer therapeutic with current application to proliferative disease and extracorporeal photopheresis (ECP) of cutaneous T Cell Lymphoma. An immunogenic role for light-activated psoralen has been reported, contributing to long-term cl...
recent studies have established that sex hormones directly or indirectly affect t and b cells and macrophages by manipulating the production of cytokines. in this study the possibility of the effect of 5a-dht on macrophage (mφ) nitric oxide (no) release via interleukin-l, 6 (ll-1β, il-6) or tumor necrosis factor-a (tnfα) was investigated. the endogenous cytokines il-1β, il-6 and tnf-α were neut...
Recent studies have established that sex hormones directly or indirectly affect T and B cells and macrophages by manipulating the production of cytokines. In this study the possibility of the effect of 5a-DHT on macrophage (MΦ) nitric oxide (NO) release via interleukin-l, 6 (lL-1β, IL-6) or tumor necrosis factor-a (TNFα) was investigated. The endogenous cytokines IL-1β, IL-6 and TNF-α were ...
Monoclonal antibodies developed against immunogenic proteins (Tumor Specific Antigens/TSA's) that are expressed in human cancers, display a unique behavioral pattern. They appear to serve in a dual role. This includes the early recognition of these immunogenic membrane proteins that can serve as diagnostic markers, and the targeting of such markers for the destruction of the tumor, primarily th...
Myocarditis is defined as inflammation of cardiac muscle with or without myocyte necrosis. Both infectious and non-infectious aetiologies for myocarditis are known, but the most common is virus-induced myocarditis often followed by post-infectious inflammatory cardiomyopathy. Many RNA (picorna-, orthomyxo-, paramyxo-, and flaviviruses) as well as DNA (adeno-, erythro-, herpes-, and retroviruses...
IN THIS ISSUE, Stanley et al. (16a) reported sex differences of unpredictable chronic mild stress (UCMS) on vascular function. They found that BALBc/J mice subjected to UCMS [reported to induce depression in rodents (9, 10)] demonstrate impairment in endothelium-dependent dilation and that the symptoms of stress/depression were more severe in females than males but that endothelium-dependent di...
We have previously demonstrated (A. E. Pegg, Cancer Res., 50: 6119–6129, 1990) that O-benzylguanine (OBG) enhances nitrosourea, temozolomide, and cyclophosphamide activity in malignant glioma xenografts growing in athymic nude mice. More recently, we have demonstrated (V. J. Patel et al., Clin. Cancer Res., 6: 4154–4157, 2000; P. Pourquier et al., Cancer Res., 61: 53–58, 2001) that the combinat...
s of the 19th Annual Congress of the SBRA, Búzios, RJ, 05-08 August 2015 tes fertilization among women performing IVF/ICSI. Methods: A case-control study was performed. The population comprised women with diagnosis of endometriosis, with or without endometrioma cysts, presenting to IVF/ ICSI procedures. Risk (Odds Ratio – OR) of endometrioma to generate fragmented embryos (B/C/D) or to affect f...
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