A conserved insulin-like pathway modulates both aging and pathogen resistance in Caenorhabditis elegans. However, the specific innate effector functions that mediate this pathogen resistance are largely unknown. Autophagy, a lysosomal degradation pathway, plays a role in controlling intracellular bacterial pathogen infections in cultured cells, but less is known about its role at the organismal...

www.chestpubs.org pathogen and 332 patients with no identifi ed pathogen ( Table 1 ) and found no association. Bacterial documentation of our population was representative of pathogens isolated in patients with severe CAP. A part of unidentifi ed pathogens might have been viral pneumonia, which is not usually searched in clinical practice. 4 These results showing thrombocytopenia for a high pe...

Many bacterial pathogens manipulate the host cell cytoskeleton during infection. Such cytoskeletal modulation can occur at several points of contact between the pathogen and the host, and involves extracellular receptors, intracellular signal transduction and cytoskeletal proteins themselves. The field of bacterial pathogenesis has progressed dramatically over the past decade, such that structu...

pantoea ananatis is an important pathogen causing bacterial center rot in onion. isolated strains from onion soft rot bulbs based on morphological characteristics were tested for hypersensitivity reaction on tobacco. pathogenic strains underwent some biochemical tests which detected the presence of p. ananatis, based on rna16s sequencing, this result was confirmed. symptoms were reproduced by i...

in this study, zinc oxide nanoparticles (znonps) were synthesized by chemical method and their antibacterial efficiency against a clinical isolate of staphylococcus aureus was studied. the zinc oxide nanoparticles have shown a commendable inhibition effect on the growth of most notorious bacterial pathogen s.aureus. the nanoparticles size and shapes were characterized by transmission electron m...

Rapid and accurate identification of mastitis pathogens is important for disease control. Bacterial culture and isolate identification is considered the gold-standard in mastitis diagnosis but is time-consuming and results in many culture-negative samples. Identification of mastitis pathogens by PCR has been proposed as a fast and sensitive alternative to bacterial culture. The results of bacte...