نتایج جستجو برای: b3 and glu
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Proof: We proved in class (Proposition 2.4.1) that there is at least one triangle-or-anti-triangle, call its vertices {a1, a2, a3}. There are at least three additional distinct vertices, b1, b2, and b3. If all of b1, b2, and b3 are adjacent to each other, then {b1, b2, b3} is a triangle. If none of b1, b2, and b3 is adjacent to any other, then {b1, b2, b3} is an anti-triangle. Assume without lo...
EphA4, an Ephrins tyrosine kinase receptor, behaves as a dependence receptor (DR) by triggering cell apoptosis in the absence of its ligand Ephrin-B3. DRs act as conditional tumor suppressors, engaging cell death based on ligand availability; this mechanism is bypassed by overexpression of DRs ligands in some aggressive cancers. The pair EphA4/Ephrin-B3 favors survival of neuronal progenitors o...
Connective tissue is highly susceptible to imbalances induced by diabetes. Diabetes-related osteopenia, decreased bone strength etc. may be associated with altered metabolism of various collagens: Although it is assumed that alterations in collagen amino acids (AA) may strongly affect protein properties andphysiological functions, however, very limited evidences are present at the moment regard...
In this work, biodegradable macroporous stimuli-responsive polypeptide hydrogels based on l-glutamic acid (Glu) and its copolymers with equimolar amounts of l-phenylalanine (Phe) or l-lysine (Lys) were prepared by deprotection the corresponding organogels under acidic conditions. The synthesized ring-opening polymerization N-carboxyanhydride (NCA) derivatives ?-amino acids in oil-in-oil high-in...
High molecular weight glutenin subunits (HMW-GSs) play a major role in determining the dough quality of wheat. As D genome donor hexaploid wheat, Aegilops tauschii is an important genetic resource for wheat breeding. In present study, novel HMW-GSs from Ae. was identified and designated as Glu-Dt1. Multiple sequence alignment indicated that one cysteine mutated into arginine y-type subunit. Sit...
The contents of GABA, glutamine (Glu) and asparagine (Asp) acids as well as activities of glutamatdecarboxylase (GDK; CF 4.1.1.15) and 4-aminobutirat: 2-oxoglutarataminotransferase (GABA-T: CF 2.6.1.19) in brain cortex, cerebellum, brainstem and hypothalamus under impact of testosterone propionate at a dose of 5 mg/100 g of alive weight of adult albino male rats in spring and autumn were studie...
BACKGROUND Thymic carcinoma (TC) is a rare type of malignant neoplasm that develops in the anterior mediastinum and associated with poor prognosis. Type B3 thymoma (B3) occasionally demonstrates malignant tumor characteristics, especially in the advanced stage. We investigated the expressions of tumor-related genes in resected TC and B3 specimens. METHODS TC and B3 specimens resected from 199...
Ephrin receptors (Ephs) are reported to control metastatic signaling of non-small cell lung cancer (NSCLC) and other tumors. Here we show for the first time that blocking expression of the Eph ligand Ephrin B3 inhibits NSCLC cell migration and invasion. We demonstrate that Ephrin B3 directly binds the EphAs EphA2, EphA3, EphA4, and EphA5. EphA2 Ser897 was previously shown to drive migration pro...
BACKGROUND In intestinal epithelium, tyrosine kinase receptor Ephrin B3 (Eph B3) maintains the architecture of the crypt-villus axis by repulsive interaction with its ligand ephrin-B1. While loss of Eph B3 is linked to colorectal cancer initiation, overexpression of Eph B3 in cancer cell lines inhibits growth and induces functional changes with decreased mesenchymal and increased epithelial mar...
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