نتایج جستجو برای: azf region
تعداد نتایج: 538164 فیلتر نتایج به سال:
Despite the well-established role of the human serotonin transporter (hSERT) in the treatment of depression, the molecular details of antidepressant drug binding are still not fully understood. Here we utilize amber codon suppression in a membrane-bound transporter protein to encode photocrosslinking unnatural amino acids (UAAs) into 75 different positions in hSERT. UAAs are incorporated with h...
the caspian sea contains great resources of oil and gas. the caspian sea is a 700- mile- long body of water in central asia, land located between azerbaijan, iran, kazakhstan, russia and turkmenistan. iran was challenges and opportunities in the caspian region. key question in this thesis includes three section that first question, opportunities of iran in the caspian region, second question ch...
The natural transmission of microdeletions of the Y chromosome is occasionally reported in the literature. Here we describe the natural transmission of a partial AZFb deletion over three generations. PCR amplification of several sequence tagged site markers in the three AZF regions of the Y chromosome was carried out in a patient with oligoasthenoteratozoospermia, his father and his naturally c...
زمینه و هدف: نواحی حاوی فاکتورهای آزوسپرمی (azf) واقع در بازوی بلند کروموزوم y، دارای ژن هایی است که نقش و عملکرد خاص آنها در اسپرماتوژنز و باروری به طور کامل مشخص نشده است؛ از این رو، شناخت ارتباط بین ریزحذف های نواحی azf با باروری مردان؛ تشخیص، درمان و مشاوره ژنتیک را مقدور می سازد. هدف از انجام این مطالعه، بررسی ریزحذف های کروموزوم y در بیماران مبتلا به ناباروری اولیگواسپرمی و آزواسپرمی غیرا...
Microdeletions in the AZF region of the Y chromosome are among the most frequent genetic causes of male infertility, although the specific role of the genes located in this region is not fully understood. AZFa and AZFb deletions impair spermatogenesis since no spermatozoa are found in the testis. Deletions of the AZFc region, despite being the most frequent in azoospermic patients, do not corre...
Bovine adrenal zona fasciculata (AZF) cells express a noninactivating K+ current (IAC) that is inhibited by adrenocorticotropic hormone (ACTH) at picomolar concentrations. Inhibition of IAC may be a critical step in depolarization-dependent Ca2+ entry leading to cortisol secretion. In whole-cell patch clamp recordings from AZF cells, we have characterized properties of IAC and the signalling pa...
The whole cell version of the patch clamp technique was used to identify and characterize voltage-gated Ca2+ channels in enzymatically dissociated bovine adrenal zona fasciculata (AZF) cells. The great majority of cells (84 of 86) expressed only low voltage-activated, rapidly inactivating Ca2+ current with properties of T-type Ca2+ current described in other cells. Voltage-dependent activation ...
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