azf region

نتایج جستجو برای: azf region

تعداد نتایج: 538164 فیلتر نتایج به سال:

Investigation of AZF microdeletions in patients with Klinefelter syndrome

Journal: :Genetics and Molecular Research 2015

Genetically encoded photocrosslinkers locate the high-affinity binding site of antidepressant drugs in the human serotonin transporter

2016

Hafsteinn Rannversson Jacob Andersen Lena Sørensen Benny Bang-Andersen Minyoung Park Thomas Huber Thomas P. Sakmar Kristian Strømgaard

Despite the well-established role of the human serotonin transporter (hSERT) in the treatment of depression, the molecular details of antidepressant drug binding are still not fully understood. Here we utilize amber codon suppression in a membrane-bound transporter protein to encode photocrosslinking unnatural amino acids (UAAs) into 75 different positions in hSERT. UAAs are incorporated with h...

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فرصتها و چالشهای ایران در منطقه خزر

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه علامه طباطبایی 1389

احمد واعظ گلیان, علی امامی میبدی, مصطفی ملکوتیان,

the caspian sea contains great resources of oil and gas. the caspian sea is a 700- mile- long body of water in central asia, land located between azerbaijan, iran, kazakhstan, russia and turkmenistan. iran was challenges and opportunities in the caspian region. key question in this thesis includes three section that first question, opportunities of iran in the caspian region, second question ch...

15 صفحه اول

Natural transmission of a partial AZFb deletion of the Y chromosome over three generations: case report.

Journal: :Human reproduction 2002

C Rolf J Gromoll M Simoni E Nieschlag

The natural transmission of microdeletions of the Y chromosome is occasionally reported in the literature. Here we describe the natural transmission of a partial AZFb deletion over three generations. PCR amplification of several sequence tagged site markers in the three AZF regions of the Y chromosome was carried out in a patient with oligoasthenoteratozoospermia, his father and his naturally c...

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بررسی مولکولی حذف های کروموزوم y در نواحی azf بیماران مبتلا به آزواسپرمی و اولیگواسپرمی غیر انسدادی مراجعه کننده به مرکز ناباروری منتصریه مشهد

ژورنال: :مجله علمی دانشگاه علوم پزشکی بیرجند 0

معصومه وکیلی ازغندی masoume vakili azghandi department of animal science, faculty of agriculture, ferdowsi university of mashhad, mashhad, iranگروه علوم دامی، دانشکده کشاورزی، دانشگاه فردوسی مشهد، مشهد، ایران. محمدرضا نصیری mohammad reza nassiri department of animal science, faculty of agriculture, ferdowsi university of mashhad, mashhad, iranگروه علوم دامی، دانشکده کشاورزی، دانشگاه فردوسی مشهد، مشهد، ایران؛ علی شمسا ali shamsa department of urology, faculty of medicine, mashhad university of medical sciences, mashhad, iranگروه اورولوژی، دانشکده پزشکی، دانشگاه علوم پزشکی و خدمات درمانی مشهد، مشهد، ایران. محسن جلالی mohsen jalali department of urology, faculty of medicine, montaseriye infertility center, mashhad, iranگروه اورولوژی، دانشکده پزشکی، مرکز ناباروری منتصریه، مشهد، ایران. محمد مهدی شریعتی mohammad mahdi shariati department of animal science, faculty of agriculture, ferdowsi university of mashhad, mashhad, iranگروه علوم دامی، دانشکده کشاورزی، دانشگاه فردوسی مشهد، مشهد، ایران.

زمینه و هدف: نواحی حاوی فاکتورهای آزوسپرمی (azf) واقع در بازوی بلند کروموزوم y، دارای ژن هایی است که نقش و عملکرد خاص آنها در اسپرماتوژنز و باروری به طور کامل مشخص نشده است؛ از این رو، شناخت ارتباط بین ریزحذف های نواحی azf با باروری مردان؛ تشخیص، درمان و مشاوره ژنتیک را مقدور می سازد. هدف از انجام این مطالعه، بررسی ریزحذف های کروموزوم y در بیماران مبتلا به ناباروری اولیگواسپرمی و آزواسپرمی غیرا...

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AZF deletions in Indian populations: original study and meta-analyses

Journal: :Journal of Assisted Reproduction and Genetics 2020

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High-Throughput Screening for Spermatogenesis Candidate Genes in the AZFc Region of the Y Chromosome by Multiplex Real Time PCR Followed by High Resolution Melting Analysis

2014

Evguenia Alechine Daniel Corach

Microdeletions in the AZF region of the Y chromosome are among the most frequent genetic causes of male infertility, although the specific role of the genes located in this region is not fully understood. AZFa and AZFb deletions impair spermatogenesis since no spermatozoa are found in the testis. Deletions of the AZFc region, despite being the most frequent in azoospermic patients, do not corre...

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Adrenocorticotropic hormone and cAMP inhibit noninactivating K+ current in adrenocortical cells by an A-kinase-independent mechanism requiring ATP hydrolysis

Journal: :The Journal of General Physiology 1996

J J Enyeart B Mlinar J A Enyeart

Bovine adrenal zona fasciculata (AZF) cells express a noninactivating K+ current (IAC) that is inhibited by adrenocorticotropic hormone (ACTH) at picomolar concentrations. Inhibition of IAC may be a critical step in depolarization-dependent Ca2+ entry leading to cortisol secretion. In whole-cell patch clamp recordings from AZF cells, we have characterized properties of IAC and the signalling pa...

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Voltage-gated transient currents in bovine adrenal fasciculata cells. I. T-type Ca2+ current

Journal: :The Journal of General Physiology 1993

B Mlinar B A Biagi J J Enyeart

The whole cell version of the patch clamp technique was used to identify and characterize voltage-gated Ca2+ channels in enzymatically dissociated bovine adrenal zona fasciculata (AZF) cells. The great majority of cells (84 of 86) expressed only low voltage-activated, rapidly inactivating Ca2+ current with properties of T-type Ca2+ current described in other cells. Voltage-dependent activation ...

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Azoospermia factor (AZF) and male infertility

2017

Eitetsu Koh Ho-Su Sin Masato Fukushima Mikio Namiki

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