IMPORTANCE Myopia is a significant public health problem, making it important to determine whether a bifocal spectacle treatment involving near prism slows myopia progression in children. OBJECTIVE To determine whether bifocal and prismatic bifocal spectacles control myopia in children with high rates of myopia progression and to assess whether the treatment effect is dependent on the lag of ...

Axial myopia is a risk factor for the development of many concomitant pathological conditions, including those likely to lead an irreversible loss visual functions. Until now, specialists disagree about terminology and approaches classification myopia. We propose critical analysis state-of-the-art research use them offer, definitions such conditions as “myopic macular degeneration (myopic macul...

PURPOSE To investigate the role of scleral creep in the axial elongation of chick and tree shrew eyes with induced myopia. METHODS Form-deprivation myopia was induced with a diffusing occluder worn over one eye. Scleral samples from the posterior pole and equatorial regions of myopic, contralateral (control), and age-matched normal chick and tree shrew eyes were loaded in vitro with a force o...

Visual environment plays an important role in the occurrence of myopia. We previously showed that the different flashing lights could result in distinct effects on the ocular growth and development of myopia. CCN2 has been reported to regulate various cellular functions and biological processes. However, whether CCN2 signaling was involved in the red flashing light-induced myopia still remains ...

PURPOSE To determine the association between ocular dominance and degree of myopia in patients with anisometropia. METHODS Fifty-five subjects with anisometropic myopia were recruited. None of them had amblyopia. Refractive error and axial length were measured in each subject. Ocular dominance was determined using the hole-in-the-card test and convergence near-point test. RESULTS There was ...

Previous theories of myopia development involved subtle and complex processes such as the sensing and analyzing of chromatic aberration, spherical aberration, spatial gradient of blur, and spatial frequency content of the retinal image. However, these theories have not been able to explain all the diverse experimental results, which has been accomplished by our newly proposed incremental retina...

PURPOSE To investigate the effect of ocular dominance on myopia development. METHODS One hundred seventy-eight myopic children (age range, 7-13 years) were recruited for a 2-year longitudinal study. The development of myopia was evaluated by the change of objective refractive error, determined with cycloplegic autorefraction, and axial length, determined with A-scan ultrasonography. Ocular do...

PURPOSE Guinea pigs have been increasingly used as an animal model for experimental myopia. Infant guinea pigs are susceptible to recovery from myopia within 2 weeks of form deprivation. This study investigated whether adolescent guinea pigs are susceptible to recovery from myopia after a longer period of form deprivation. METHOD Twenty-two guinea pigs (age of 3 weeks) were randomly assigned ...

We report a case of 43 years old women who present myopic CNV (A) causing an acute vision loss. That has not been treated at time causing a chorioretinal atrophy as the angiography (B) and her Optical Coherence Tomography (OCT) (C) shows. High myopia is a major cause of legal blindness in many countries, especially in young people. Itis defined as a refraction of at least -6.00 diopters and/or ...

To shed light on the potential role of the phenomenon of form-deprivation myopia in normal refractive development, we investigated the degree of image degradation required to produce axial myopia in rhesus monkeys. Starting at about 3 weeks of age, diffuser spectacle lenses were employed to degrade the retinal image in one eye of 13 infant monkeys. The diffusers were worn continuously for perio...