A substantial proportion of hitherto unexplained respiratory tract illnesses is associated with human metapneumovirus (hMPV) infection. This virus also was found in patients with severe acute respiratory syndrome (SARS). To determine the dynamics and associated lesions of hMPV infection, six cynomolgus macaques (Macaca fascicularis) were inoculated with hMPV and examined by pathological and vir...

The clinical spectrum of 69 episodes of metapneumovirus pediatric infection (55 episodes caused by genotype A and 14 episodes caused by genotype B) was analyzed. Diagnosis of pneumonia was more common and the illness severity index (determined on the basis of need for hospitalization, oxygen saturation <90%, and intensive care unit stay) was higher for patients with metapneumovirus genotype A i...

Human metapneumovirus pneumonia, most commonly found in children, was diagnosed in an adult with encephalitis. This case suggests that testing for human metapneumovirus RNA in nasopharyngeal aspirate and cerebrospinal fluid samples should be considered in adults with encephalitis who have a preceding respiratory infection.

conclusions infection with hmpv and rsv are most frequent infections among pediatric patients with respiratory tract symptoms. coinfection with these viruses may exacerbate the clinical symptoms and increase hospitalization rates, especially in children younger than one year old. results the hmpv and rsv were detected in 44 (15.7%) and 84 (30.0%) samples, respectively. coinfection with both vir...

Introducción: Los virus respiratorios son una de las causas más frecuentes exacerbaciones asmáticas en el niño, pero además cada vez hay evidencia que infecciones respiratorias virales etapas precoces la vida están relacionadas con desarrollo asma a medio y largo plazo Objetivo: analizar relación del Metapneumovirus, Bocavirus Rinovirus patogenia exacerbación otras afecciones niños. Métodos: La...

We examined 10,025 respiratory samples collected for 4 years (2001-2004) and found a 7.1% average annual incidence of human metapneumovirus. The epidemic peak of infection was late winter to spring, and genotyping showed a change in predominant viral genotype in 3 of the 4 years.