Imprinting ensures that the infant forms the caregiver attachment necessary for altricial species survival. In our mammalian model of imprinting, neonatal rats rapidly learn the odor-based maternal attachment. This rapid learning requires reward-evoked locus ceruleus (LC) release of copious amounts of norepinephrine (NE) into the olfactory bulb. This imprinting ends at postnatal day 10 (P10) an...

Angiosarcoma is a rare and generally fatal tumor composed of aberrant cells of endothelial origin. Because of its infrequency in humans, very little is known about the growth requirements of this vascular sarcoma. Unlike the rapidly proliferating solid tumors from which they are isolated from, many of the established angiosarcoma cell lines exhibit less than robust growth in culture and often f...

OBJECTIVE To explore attachment narratives in children diagnosed with reactive attachment disorder (RAD). METHOD We compared attachment narratives, as measured by the Manchester Child Attachment Story Task, in a group of 33 children with a diagnosis of RAD and 37 comparison children. RESULTS The relative risk (RR) for children with RAD having an insecure attachment pattern was 2.4 (1.4-4.2)...

We study the relationship between divorce rates and female labor force attachment in the US. Recent cross-sectional evidence from US states displays a robust negative correlation between divorce and the rate of married female labor force participation. We suggest that this pattern can be explained at least partly by increased bargaining flexibility within two-earner as against one-earner househ...

The three papers in this special issue represent an important advance in the effort to understand people's attachment to place. Economic factors do not provide an adequate explanation; it is necessary to seek less tangible influences. There are grounds for looking to the physical setting, and especially the natural environment available to residents. Access to other resources may also be import...

Although the role of nucleus accumbens (NAcc) dopamine (DA) in reward learning has been extensively studied, few investigations have addressed its involvement in learning socially relevant information. Here, we have examined the involvement of NAcc DA in social attachment of the "monogamous" prairie vole (Microtus orchrogaster). We first demonstrated that DA is necessary for the formation of so...

This study examines the effect of race on place attachment to wildland areas. It is generally assumed that African Americans have a more negative impression of wildlands, compand to white ethnic groups. Studies from past decades report that blacks show less aesthetic preference for wildland, unstructured environments and are also less environmentally aware than whites. While it is assumed that ...

Using a cell culture model where virus is bound to the extracellular matrix (ECM) prior to cell surface binding, we determined that human papillomavirus type 16 (HPV16) utilizes ECM resident laminin (LN) 332 as an attachment receptor for infectious entry. In presence of LN332, soluble heparin can function as ligand activator rather than competitive inhibitor of HPV16 infection. We also show tha...

Pharmacological studies in prairie voles have suggested that the neuropeptides oxytocin and vasopressin play important roles in behaviors associated with monogamy, including affiliation, paternal care, and pair bonding. Our laboratory has investigated the cellular and neuroendocrine mechanisms by which these peptides influence affiliative behavior and social attachment in prairie voles. Monogam...