Atopic dermatitis (AD) is a chronic inflammatory skin disease, characterized by the appearance of redness, rash and itching. The prevalence in adults was around 1-3%. Due to relapse, general there has been no satisfactory management AD. This Retrospective study new adult atopic patients Dr. Soetomo General Academic Hospital Surabaya. data were collected from medical records. Out 243 AD patient ...

OBJECTIVE To assess the impact of atopic dermatitis (AD) on the quality of life (QoL) of Saudi infants and children using a validated/culturally adapted Arabic version of the infants` dermatitis quality of life (IDQoL) index, and to investigate the correlation between IDQoL and disease severity. METHODS This study was performed in the Dermatology Clinics and Hospitals affiliated to Qassim Uni...

background atopic dermatitis (ad), often called eczema or atopic eczema is a very common skin disease; ad looks different in infants, children, and adults. the aim of this study was to determine the prevalence of the disease in kurdistan province. materials and methods cross-sectional study using written questionnaires isaac  where 4,000 students in two age groups 7-6 and 14 -13 years in the pr...

Atopic dermatitis (AD) is characterized by skin inflammation, barrier dysfunction and chronic pruritus. In this review, recent advances in the pathogenesis of AD are summarized. Clinical efficacy of the anti-IL-4 receptor antibody dupilumab implies that type 2 cytokines IL-4 and IL-13 have pivotal roles in atopic inflammation. The expression of IL-4 and IL-13 as well as type 2 chemokines such a...

b ac k gro und : atopic dermatitis (ad) is a prevalent chronic disease in children aging from 6 months to 12 years old. recent studies have shown a positive effect of prebiotics in the prevention and treatment of ad. the mechanism of this effect has not been clearly established. the objective of this study was to investigate the effect of supplementation of prebiotic on serum immunoglobulin e (...

BACKGROUND & OBJECTIVES Atopic diseases, including atopic dermatitis (AD), allergy and asthma, are complex diseases resulting from the effect of multiple genetic and interacting environmental factors on their pathophysiology. The genetic basis is incompletely understood; however, recent studies have shown an association between loss-of-function variants of the filaggrin gene (FLG) and atopic de...

Atopic dermatitis (AD) has been sub-classified into extrinsic and intrinsic types according to the presence or not of allergen-specific IgE antibodies. Although total serum IgE levels are frequently elevated in AD, their potential to predict allergen-specific IgE (asIgE) has rare ly been studied. We investigated 103 children with AD and suspected allergen-specific sensitization. A thorough clin...

The value of CD30 and the soluble circulating fragment of CD30 (sCD30) for atopic dermatitis (AD) remains unclear. In particular, little is known about the effects of age, duration of disease and Scoring Atopic Dermatitis index (SCORAD) on the levels of serum sCD30 in patients affected by AD. In the present study, we have analysed serum sCD30 levels of adult patients affected by AD. The study's...

The underlying mechanisms of skin inflammation in atopic dermatitis (AD) are not completely understood but inflammatory cell activation and dysregulated cytokine production appear to play a critical role in pathogenesis of AD. Inducible nitric oxide synthase (iNOS) is expressed by dermal endothelial cells and perivascular inflammatory cells in the atopic skin lesion, suggesting the involement o...