The effects of a 3-month physical training programme on airway inflammation and clinical outcomes were studied in school-aged children with asthma. Subjects with persistent allergic asthma (aged 12.7+/-3.4 yrs; n = 34) were randomly allocated into training and control groups. Exercise consisted of twice-weekly 50-min sessions for 12 weeks. Inflammation was assessed by levels of exhaled nitric o...

OBJECTIVE To assess children and adolescents diagnosed with mild intermittent or mild persistent asthma, in terms of their aerobic capacity between attacks. METHODS We included 33 children and adolescents recently diagnosed with asthma (mild intermittent or mild persistent) and 36 healthy children and adolescents. Those with asthma were evaluated between attacks. All participants underwent cl...

OBJECTIVE The aim of this study was to investigate factors related to insomnia in a cohort of people with asthma. DESIGN This secondary analysis utilized cross-sectional data from the Norwegian Nord-Trøndelag Health Study, a population-based health survey (n=50,807). PARTICIPANTS We used self-reported data from 1,342 men and women with a physician-confirmed asthma diagnosis ranging in age f...

As the existence of a late reaction in exercise induced asthma is controversial, peak expiratory flow (PEF) was measured for up to 13 hours after a running test in 404 consecutive young male army conscripts undergoing assessment of their asthma. In 294 subjects (73%) the immediate post-exercise fall in PEF was 10% or more; the mean (SD) fall in PEF in this group was 27% (15%). Nine patients wit...

cromolyn sodium, a mast cell stabilizing agent, provides an immediate protective effect against the exercise-induced bronchoconstriction while being used before the exercise. however, cromolyn is ineffective in reversing asthmatic bronchospasm; it is used as a maintenance therapy and has a prophylactic role in chronic asthma.    the purpose of this study was to determine the extent of change in...

The aim of this systematic review was to determine if diaphragmatic breathing exercise improves quality of life (QoL) in asthma. Electronic databases were searched for randomized controlled trials (RCTs). Data were extracted and risk of bias was assessed by two independent reviewers. Three RCTs were eligible for inclusion (254 subjects). Two studies compared diaphragmatic breathing exercise to ...

A treadmill exercise test was carried out on 154 male subjects aged 15-25 years who gave a history of mild asthma in childhood, and on 31 similarly aged control subjects. The results were expressed as an exercise lability index, (ELI), based on measurement of FEV. The mean ELI of the control group was 7.6%, range 2.9-12.2% and a positive result in the asthma subjects was an ELI greater than 15%...

Konig, P., and Godfrey, S. (1973). Archives of Disease in Childhood, 48, 513. Prevalence ofexercise-induced bronchial lability in families ofchildren with asthma. Exercise tests and skin tests were performed in 65 members of the families of 12 children with asthma. A positive response to skin and exercise challenge frequently, but not invariably, occurred together. Abnormal exercise-induced bro...

It has been proposed that exercise induced asthma is a result of "rapid expansion of the blood volume of peribronchial plexi" (McFadden ER, Lancet 1990;335:880-3). This hypothesis proposes that the development of exercise induced asthma depends on the thermal gradient in the airways at the end of hyperpnoea. The events that result in exercise induced asthma are vasoconstriction and airway cooli...