micrornas participate in the regulation of asthma, the goal of this study is to summarize recent researches on the roles of micrornas in the pathogenesis of asthma. a review of the english medical literatures was conducted by searching pubmed for studies concerning asthma and micrornas. the results of the present study indicate that micrornas play important roles in regulating asthma immune res...

Background: Pediatric bronchial asthma is associated with considerable morbidity. The study was carried out to examine the association of Human Leukocyte Antigen (HLA)- Class II with the disease as we found no similar study on Asian Indian population. Objective: To define the HLA-Class II antigens in Asian Indian pediatric patients with asthma. Methods: A total of 103 children with asthma and 1...

Asthma and chronic obstructive pulmonary disease (COPD) are highly prevalent chronic diseases in the general population. Both are characterized by similar mechanisms: airway inflammation, airway obstruction, and airway hyperresponsiveness. However, the distinction between the two obstructive diseases is not always clear. Multiple epidemiological studies demonstrate that in elderly people with o...

The response to glucocorticoids (GCs) therapy classifies severe refractory asthma (SRA) and mild asthma, so the glucocorticoid receptors (GCRs) gene expression may be involved in SRA pathogenesis. Thus, it is aimed to compare the expression levels of two GCR isoforms (GCRα and GCRβ) in SRA, mild asthmatics, and healthy controls. Total RNA was isolated from the peripheral blood mononuclear lymph...

  Background: Industrialization and urbanization had a devastating impact on public health and caused an increase in health related morbidity and mortality. In fact, asthma is a chronic condition which is considered as one of the significant challenges of public health. In this study, we investigated the association of air pollution and weather conditions with excess emergency ward admissions o...

A 24 years old man with known history of asthma came acute presentation ascending weakness for4 days following flu like symptoms and worsening asthma. His complete blood counts showed elevated eosinophil count. Nerve conduction neuropathy. Diagnosed Churg Strauss syndrome due to presence asthma, eosinophilia, neuropathy pulmonary infiltrates. is systemic eosinophilic vasculitis involving multip...

for better management of asthma it is essential that patients adjust their treatment according to the medical plan developed by the health care professionals. to achieve this goal, patients should assess the severity of their disease regularly. the purpose of this study was to determine the effect of regular measurement of peak expiratory flow and patient education on self management of asthma....

Severe asthma is defined as either refractory to traditional therapies or controlled only with that have intolerable side effects. Biological agents are known offer treatment alternatives patients type 2 inflammation severe asthma. We describe the case of a woman long history asthma, uncontrolled symptoms and need systemic corticosteroid therapy prevailing features, respiratory failure differen...