Meta-analysis, a statistical tool for combining results across studies, is becoming popular as a method for resolving discrepancies in genetic association studies. Persistent difficulties in obtaining robust, replicable results in genetic association studies are almost certainly because genetic effects are small, requiring studies with many thousands of subjects to be detected. In this article,...

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BACKGROUND Professionalism should be included as a fundamental component in the curriculum of undergraduate as well as graduate students of Medicine. Future physicians should be aware of the attributes that a professional should possess. AIM To analyze the ideal medical doctor attributes from the point of view of physicians and students of Medicine. MATERIAL AND METHODS One hundred four phy...

GRD is an algorithm for k-most interesting rule discovery. In contrast to association rule discovery, GRD does not require the use of a minimum support constraint. Rather, the user must specify a measure of interestingness and the number of rules sought (k). This paper reports efficient techniques to extend GRD to support mining of negative rules.

Nicolas Kieffer, Laurent Poirel, Lucinda J. Bessa, Ana Barbosa-Vasconcelos, Paulo Martins da Costa, Patrice Nordmann “Emerging Antibiotic Resistance” Medical and Molecular Microbiology Unit, Department of Medicine, Faculty of Science, University of Fribourg, Fribourg, Switzerland; ICBAS, Abel Salazar Institute for the Biomedical Sciences, University of Porto, Porto, Portugal; CIIMAR, Interdisci...

Genome-wide association studies (GWAS) have quickly become the norm in dissecting the genetic basis of complex diseases. Family-based association approaches have the advantages of being robust to possible hidden population structure in samples. Most of these methods were developed with limited markers. Their applicability and performance for GWAS need to be examined. In this report, we evaluate...

Leveraging upon product and process families has been well recognized as an important area for manufacturers to exploit mass production efficiency, wherein the linchpin of managing variety propagation from design to production lies in the mapping relationships between product differentiation and process variation. Taking advantage of knowledge discovery from historical data, this paper applies ...

Itemsets, which are treated as intermediate results in association mining, have attracted significant research due to the inherent complexity of their generation. However, there is currently little literature focusing upon the interactions between itemsets, the nature of which may potentially contain valuable information. This paper presents a novel tree-based approach to discovering itemset in...