Lymphomas were reported to be induced in rats in bioassays of aspartame, methyl-tertiary-butyl ether (MTBE), and other chemicals conducted by a nonprofit cancer research organization. European regulatory authorities concluded that lymphomas in the aspartame study were caused by Mycoplasma pulmonis and suggested that this also was the case for the MTBE bioassay. To assess the role of M. pulmonis...

Taste evaluation technology has been developed by several methods, such as sensory tests, electronic tongues and a taste sensor based on lipid/polymer membranes. In particular, the taste sensor can individually quantify five basic tastes without multivariate analysis. However, it has proven difficult to develop a sweetness sensor, because sweeteners are classified into three types according to ...

Aspartame is an artificial sweetener used as a substitute for sugar in many soft drinks, beverages and some foods. It is a combination of phenylalanine, aspartic acid and methanol. It has a caloric value of 17 KJ per gram like other protein substance. An Acceptable Daily Intake (ADI) of aspartame is 40-50 mg/kg body weight/day; it helps the diabetics to improve their quality of life. Higher con...

It has been suggested that the use of nonnutritive sweeteners (NNSs) can lead to weight gain, but evidence regarding their real effect in body weight and satiety is still inconclusive. Using a rat model, the present study compares the effect of saccharin and aspartame to sucrose in body weight gain and in caloric intake. Twenty-nine male Wistar rats received plain yogurt sweetened with 20% sucr...

Re. DRAFT Scientific Opinion on the re-evaluation of aspartame (E 951) as a food additive Further to my telephone conversations and email exchange with Christophe Wolff on 12 th and 13 th February, I am now sending you this letter as my detailed response to the EFSA Panel's DRAFT Scientific Opinion on the re-evaluation of aspartame (E 951) as a food additive, which was issued on 8 th January 20...

Encoding finite linear CSPs as Boolean formulas and solving them by using modern SAT solvers has proven to be highly effective, as exemplified by the award-winning sugar system. We here develop an alternative approach based on ASP. This allows us to use first-order encodings providing us with a high degree of flexibility for easy experimentation with different implementations. The resulting sys...