Fourteen cases of infection with ECHO 6 virus in the Chelmsford area from August to December 1968 are described. A comparative account of the seasonal, geographical and age incidence is given, and its relationship to certain epidemiological aspects is discussed. Aseptic meningitis occurred in eleven patients, pharyngitis in seven and myalgia in five. One patient suffered from pericarditis, a ma...

INTRODUCTION Cases of idiopathic recurrent benign aseptic meningitis were first described by Mollaret. Today, herpes simplex virus (HSV) is considered the cause of most cases of Mollaret's meningitis. CASE REPORT A 40-year-old male was referred to our genitourinary medicine clinic with recurrent genital herpetic lesions. He had HSV-2-positive genital ulcers 8 years earlier. One year after the...

An epidemic of meningitis caused by ECHO virus type 4, was reported in many areas of Japan during the summer and early autumn of 1964. (1) During May to August of 1965, aseptic meningitis was prevalent chiefly in the northern parts of Kyushu. It was revealed that this was an epidemic of ECHO virus type 4. The present paper reports the results of study of this epidemic. The study is divided into...

Iatrogenic meningitis can be caused by a number of mechanisms. The recent case reports of fungal meningitis after application of epidural methylprednisolone caused warning in the medical community. Cases were caused by contaminated lots of methylprednisolone from a single compounding pharmacy. Several medications can cause meningitis by probable hypersensitivity mechanism. Neurologists should b...

BACKGROUND Increased levels of plasma nuclear and mitochondrial DNA have been reported in critically ill patients. We tested the hypothesis that plasma nuclear and mitochondrial DNA are substantially increased in acute bacterial meningitis and decrease after antimicrobial therapy, and that plasma nuclear and mitochondrial DNA levels can predict treatment outcomes. METHODS We examined serial p...

Viral infection is the most common cause of aseptic meningitis with the most frequent virus associated with aseptic meningitis being enteroviruses (coxsackievirus and echovirus). In viral meningitis, cerebrospinal fluid (CSF) shows a mild pleocytosis with a lymphocytic predominance, elevated protein, and normal glucose level. Nucleic acid amplification methods have greatly improved the detectio...

Introduction Bacterial meningitis is a known infectious disease which occurs at early ages and should be promptly diagnosed and treated. Bacterial and aseptic meningitis are hard to be distinguished. Therefore, physicians should be highly informed and experienced in this area. The main aim of this study was to suggest a system for distinguishing between bacterial and aseptic meningitis, using f...

conclusions: even, very low amount of csf-igg with good specificity (90%); could differentiate cases and controls (p = 0.000). the csf-igg test (sensitivity 70%, npv 28.8%) was weak for ruling out the m. pneumonia in cases. positive pcr was rare (2%) in csf of cases and controls but is more reliable for diagnosing the recent m. pneumonia infection. we prefer to assay the csf for both serology a...

The majority of adverse reactions of intravenous immunoglobulin (IVIG) therapy are mild, transient and self-limiting with potentially serious complications occurring in <5% of patients. IVIG-associated transient aseptic meningitis is one such rare adverse effect, which has been seldomly described in the literature. We report a case of aseptic meningitis due to IVIG therapy in a Guillain-Barré s...

BACKGROUND Kikuchi Fujimoto disease (KFD), or histiocytic necrotising lymphadenitis, is a benign and self-limiting condition characterised by primarily affecting the cervical lymph nodes. Recurrent aseptic meningitis in association with KFD is extremely rare and remains a diagnostic challenge. CASE PRESENTATION We report a 28-year-old man who presented 7 episodes of aseptic meningitis associa...