Cassie Wagner is Web Development Librarian in the Morris Library at Southern Illinois University Carbondale; e-mail: [email protected]. ©Cassie Wagner This study examines the extent to which ARL academic libraries collect graphic novels. Using a core list of 176 titles developed from winners of major comics industry awards and a library-focused “best of” list, the holdings of 111 ARL academic...

Procedural representations of control policies have two advantages when facing the scale-up problem in learning tasks. First they are implicit, with potential for inductive generalization over a very large set of situations. Second they facilitate modularization. In this paper we compare several randomized algorithms for learning modular procedural representations. The main algorithm, called Ad...

EWMA control charts designed for monitoring the variance or the mean and the variance of a normally distributed variable are either based on the log transformation of the sample variance S or provide only rough ARL results. Gan (1995), as the most prominent example for the simultaneous case, calculated ARL values precisely for X̄-lnS EWMA schemes. The results in Knoth and Schmid (2002) for X̄-S o...

Persons infected with the human immunodeficiency virus (HIV) are at increased risk for the development of malignant lymphoma.' When analyzed with molecular techniques, all of these acquired immunodeficiency syndrome (AIDS)-related lymphomas (ARL) have been shown to contain clonal rearrangements of portions of B-cell genes such as Ig heavy chain (JH) and K-lg light chain Clonal rearrangements of...

Primary cilia serve as cellular antenna for various sensory signaling pathways. However, how the sensory receptors are properly targeted to the ciliary surface remains poorly understood. Here, we show that UBC-9, the sole E2 small ubiquitin-like modifier (SUMO)-conjugating enzyme, physically interacts with and SUMOylates the C terminus of small GTPase ARL-13, the worm orthologue of ARL13B that ...

BACKGROUND AND PURPOSE AIDS-related systemic non-Hodgkin lymphoma (ARL) remains a significant cause of morbidity and mortality in patients infected with the human immunodeficiency virus (HIV-1), and leptomeningeal disease in this setting has a dismal prognosis. We investigated the utility of brain CT in determining the outcome of leptomeningeal disease, despite MR imaging being the gold standar...

Not long after the recognition of HIV as the causative agent of AIDS, it was evident that individuals infected with HIV developed lymphoma at a greater rate than the population at large. Approximately two thirds of AIDS-related lymphoma (ARL) cases are categorized as diffuse large B-cell type, with Burkitt lymphomas comprising 25% and other histologies a much smaller proportion. Typically, thes...

Cilia are microtubule-based cellular organelles that mediate signal transduction. Cilia are organized into several structurally and functionally distinct compartments: the basal body, the transition zone (TZ), and the cilia shaft. In vertebrates, the cystoprotein Inversin localizes to a portion of the cilia shaft adjacent to the TZ, a region termed the "Inversin compartment" (InvC). The mechani...

Myosinopathies have emerged as a new group of diseases and are caused by mutations in genes encoding myosin heavy chain (MyHC) isoforms. One major hallmark of these diseases is skeletal muscle weakness or paralysis, but the underlying molecular mechanisms remain unclear. Here, we have undertaken a detailed functional study of muscle fibers from Myh4(arl) mice, which carry a mutation that provok...