Several studies have shown that magnesium can be a useful tool in preventing various skin disorders. However, the mechanism remains unclear. In this study, we analyzed by which improves function, focusing on water channel aquaporin-3 (AQP3), is cutaneous functional molecule. Magnesium compounds (magnesium acetate, chloride, sulfate, and lactate) were added to human epidermal keratinocyte HaCaT ...

The purpose of this study was to compare the expression of BSC-1 (bumetanide-sensitive Na-K-2Cl cotransporter) in kidneys of spontaneously hypertensive (SHR) versus WistarKyoto (WKY) rats by immunoblotting and RT-PCR. To determine the specificity of any observed changes in BSC-1 expression, we also compared expression of the thiazide sensitive Na-Cl cotransporter (TSC), the type-3 Na-H exchange...

A refined structure of the human water channel aquaporin-1 is presented. The model rests on the high resolution X-ray structure of the homologous bacterial glycerol transporter GlpF, electron crystallographic data at 3.8 A resolution and a multiple sequence alignment of the aquaporin superfamily. The crystallographic R and free R values (36.7% and 37.8%) for the refined structure are significan...

BACKGROUND We analyzed aquaporin 4 and -1 expression in subependymomas, benign and slow growing brain tumors WHO grade I. Ten subependymoma cases were investigated, five of the fossa inferior and five of the fossa superior. METHODS AND RESULTS Using immunohistochemistry, we observed different aquaporin expression patterns depending on localization: aquaporin 4 and -1 were detected in infraten...