Apolipoprotein B is the main structural surface protein found on all beta-lipoproteins (Chylomicrons, VLDLs, IDLs and LDLs). There is a single molecule of apoB on each of those lipoproteins. It is the only apolipoprotein that is not transferablei.e. it is with the particle from its birth till its death. Beta-lipoproteins are the lipoproteins capable of trafficking cholesterol into the artery wa...

Amyloid-b peptides, through highly sophisticated enzymatic machinery, are universally produced and released in an action potential synchronized manner into the interstitial fluids in the brain. Yet no native functions are attributed to amyloid-b. The amyloid-b hypothesis ascribes just neurotoxicity properties through build-up of soluble homomeric amyloid-b oligomers or fibrillar deposits. Apoli...

BACKGROUND Lipid profiles are usually measured after fasting. We tested the hypotheses that these levels change only minimally in response to normal food intake and that nonfasting levels predict cardiovascular events. METHODS AND RESULTS We cross-sectionally studied 33 391 individuals 20 to 95 years of age from the Copenhagen General Population Study. We also studied 9319 individuals 20 to 9...

10 Background: Recent studies have shown the apolipoprotein B to apolipoprotein A1 ratio (apoB/A1) to be superior to LDL-cholesterol m 11

OBJECTIVE To determine whether prolonged infection with hepatitis B virus is associated with a lower blood cholesterol concentration. DESIGN Cross sectional study. SETTING 81 villages in rural China with a high prevalence of chronic infection with hepatitis B virus. SUBJECTS 1556 apparently healthy men aged 35-64 years, randomly selected. MAIN OUTCOME MEASURES Hepatitis B virus carrier ...

Background: Type 2 diabetes mellitus (Type DM), characterized by a relative insulin deficiency or resistance, is associated with cluster of metabolic abnormalities, which includes glucose intolerance, hypertension, unique dyslipidemia, procoagulant state, and an increase in macrovascular diseases. Aims Objectives: The present study was conducted to correlate between fasting postprandial apolipo...

A common accuracy-based standardization program is indispensable for establishing reference intervals for the clinical use of apolipoproteins. The development and distribution of reference materials and quality-control materials that do not exhibit matrix effects between methods is essential to the standardization process. We examined the suitability of lyophilized material as a common referenc...