Methods A prospective cohort study in polytrauma patients. 100 consecutive adult polytrauma patients were included. Serum level of IL-17A was measured at the day of admission to the intensive care unit (ICU). Patients were screened for the development of sepsis. Other data collection included; demographic data Abbreviated Injury Scale (AIS), APACHE II score, acute kidney injury assessed by RIFL...

AIM The aim of the current study is to assess the mortality prediction accuracy of circulating cell-free DNA (CFD) level at admission measured by a new simplified method. MATERIALS AND METHODS CFD levels were measured by a direct fluorescence assay in severe sepsis patients on intensive care unit (ICU) admission. In-hospital and/or twenty eight day all-cause mortality was the primary outcome....

BACKGROUND Neutrophil CD64 has been shown to be a promising biomarker for bacterial infection and sepsis identification. However, the prognostic value of CD64 in predicting the likelihood of survival for patients in intensive care unit (ICU) is unclear. METHODS A total of 797 patients in the ICU of Xin-Hua Hospital, Shanghai, China were enrolled. We determined the Acute Physiology and Chronic...

Methods To Collect 64 cases with severe sepsis hospitalized in SICU of the First Affiliated hospital of Sun Yat-sen University from December 2012 to December 2013, retrospectively. Monitored the dynamic changes of serum PCT, C-reactive protein(CRP), vital signs, blood routine test on the 1, 3 and 7 day after admission to SICU, the Acute Physiology and Chronic Health Evaluation II (APACHE II) sc...

BACKGROUND How to effectively use the finite resources of an intensive care unit (ICU) for neurosurgical patients is a critical decision-making process. Mortality prediction models are effective tools for allocating facilities. This study intended to distinguish the prediction power of the Acute Physiology and Chronic Health Evaluation II (APACHE II), the Simplified Acute Physiology Score II (S...

Results. Four hundred and seventy-five patients (11.2%) died in hospital after discharge from the ICU. Increasing age, time in hospital before intensive care admission, Acute Physiology and Chronic Health Evaluation II (APACHE II) score, and discharge Therapeutic Intervention Scoring System (TISS) score were independent risk factors for death after intensive care discharge. Three hundred and ei...

OBJECTIVE To evaluate whether tentative prognostic models for intensive care unit survival of multiple trauma patients could be improved by including endocrine parameters. DESIGN Prospective study. PATIENTS Eighty-three male and 11 female multiple trauma patients. MEASUREMENTS Upon admission, severity of trauma was assessed with the Acute Physiology and Chronic Health Evaluation II (APACH...

BACKGROUND Mortality predictions calculated using scoring scales are often not accurate in populations other than those in which the scales were developed because of differences in case-mix. The present study investigates the effect of first-level customization, using a logistic regression technique, on discrimination and calibration of the Acute Physiology and Chronic Health Evaluation (APACHE...

Methods Observational study performed in a 17 beds medicalsurgical ICU. Time of study was 14 months. Consecutive mechanically ventilated patients with COPD and/or cardiac failure were included. The variables analyzed were age, sex, ICU diagnosis, APACHE II at admission in ICU, fluid balance, ICU length of stay, tracheotomy, rate of reintubation. We distinguish two strategies of extubation based...

OBJECTIVES There are scarce data from India validating scoring systems used to predict outcome in patients requiring mechanical ventilation. This study prospectively compared the organ system failure (OSF), the acute physiology and chronic health evaluation (APACHE) II, and the APACHE III, scores on patients requiring mechanical ventilation in the medical intensive care unit, to predict outcome...