Aim. The side effects associated with the use of indometacin are noted by about 30-60% patients, therefore, in this context problem adverse event rate reduction is still relevant today. Cryopreserved placental extract (CEP) attracted our attention as a means pathogenetic correction ulcerogenic action indomethacin. aim paper to characterize antiulcer activity cryopreserved placenta on model indo...

Most of the medicinal agents are originated from nature and considered as a rich source for producing drugs including modern drugs. Swietenia machrophylla is one of the most important plant of the family, Meliaceae. It is planted widely in Southern Asia and in the Pacific region. This review provides information on its traditional uses, phytochemical and medicinal values. The plant extracts and...

Study was aimed to evaluate the possible antisecretory and antiulcer activity of crude bark extract of Acacia catechu and its action against indomethacin an non steroidal anti inflammatory drug (NSAID) plus pyloric ligation induced gastric ulcers in rats. Administration of crude extract of Acacia catechu (400mg/kg/day p.o.) significantly reduced ulcer index when compared with indomethacin induc...

Glycyrrhiza glabra L. is used in folk medicine for treatment of stomach disorders includingpeptic ulcers. The hydroalcoholic extract of Glycyrrhiza glabra L. (HEGG) was evaluated forantiulcerogenic activity and acute toxicity profile in mice. Various doses of HEGG (50-200mg/kg) were administered orally to animals of different groups. Omeprazole and cimetidine atdoses of 30 and 100 mg/kg were us...

Physalis minima Linn. (Family  Solanaceae) is commonly known as Ground Cherry or Sunberry. It is traditionally used as diuretic, purgative, analgesic, anthelmentic, febrifuge, vermifuge, abortificient, etc. Many steroidal lactones have been identified from the plant and it has been reported to possess antifertility, hypoglycemic, cytotoxic, antiulcer, antibacterial, anti-inflammatory, analgesi...

OBJECTIVE This study was conducted to evaluate the antiulcerogenic property of hydroalcoholic extract obtained from the leaves of Plumeria alba Linn. METHODS Antiulcer assays were performed using the protocols of ulcer induced by non-steroidal anti-inflammatory drugs, ethanol and pylorus ligation. The hydroalcoholic extract (HAPA), and various fractions of HAPA like, n-hexane extract (HPA), e...

The objective of the present study was to investigate the antiulcer activity of methanol extract of Oxalis corniculata (whole plant) using pylorus ligation and indomethacin-induced gastric ulceration in Wistar rats. The extract was preliminary evaluated for acute oral toxicity test using Organisation for Economic Co-operation and Development guidelines 423. Further, it was studied for antiulcer...