radioiodine therapy is the safest, simplest, least expensive and most effective method for treatment of hyperthyroidism. the method employed in this research was a systematic bibliographic review, in which only valid studies or the clinically detailed enough open-labeled studies using validated scales were used. iodine-131 (i-131) acts by the destructive effect of short-range beta radiation on ...

Introduction Since the introduction of thiouracil in 1943 antithyroid treatment for thyrotoxicosis has increased widely and has proved safer and more effective in carefully selected cases as the years have passed. Since 1951 carbimazole has been highly favoured in this country, being considered the least toxic agent in large-scale surveys (Burrell, Fraser & Doniach, 1956). Later (Willcox, 1962)...

Tetraethylthiuram disulfide (Antabuse) has been demonstrated to be clinically useful in treating alcoholism (1). The compound has been shown to inhibit the oxidation of acetaldehyde (2) and, further, to inhibit the action of rat liver xanthine oxidase to the extent of 71 per cent, and the succinoxidase system 100 per cent (3). Examination of the chemical structure of Antabuse indicates that it ...

A atividade antitireóidea do 6-cloropurina, in vitro, foi determinada espectrofotometricamente por estudos de formação de seu complexo com iodo. O complexo mostrou estequiometria de 1:1. A constante de formação do complexo encontrada foi 7,652 × 10 L mol, o que indicou um bom potencial de 6-cloropurina, como agente antitireóideo. Posteriores verificações mostraram mudanças nos níveis hormonais ...

This review summarizes data on the incidence of autoimmune diseases and examines prevalence antithyroid antibodies in extrathyroid diseases. In world, about 5–7% population suffers from one or another type Among six most common diseases, thyroid associated predominate. The high raises questions potential role course It is believed that are result interactions between triggers, autoantigens, gen...