In the present work a series of novel coumarin-3-carboxamides and their hybrids with the alpha-lipoic acid were designed, synthesized and tested as potent antioxidant and anti-inflammatory agents. The new compounds were evaluated for their antioxidant activity, their activity to inhibit in vitro lipoxygenase and their in vivo anti-inflammatory activity. In general, the derivatives were generall...

Diabetes mellitus is a complex and progressive metabolic disease which is associated with multiple complications. Chronic hyperglycaemia is the defining characteristic of diabetes mellitus. Hyperglycaemia leads to generation of free radicals and induces oxidative stress, which has become the chief factor that leads to diabetic complications. This review supports the use of antioxidant vitamins ...

Numerous studies have been focused on natural anticarcinogenic agents. Many antioxidants have been identified as anticarcinogens. Antimutagens have also been proposed as cancer chemopreventive agents. The use of natural products as anticancer has a long history that began with traditional medicine. The aim of this study was to evaluate cytotoxicity and antioxidant activity of twenty-three plant...

In the last decade, determination of antioxidant activity and the total content of antioxidants in foods, beverages, herbal extracts and dietary supplements has been in wide demand [1,2]. This activity is related with compounds capable of protecting a biological system against the potentially harmful effect of processes or reactions than cause excessive oxidation, involving reactive oxygen spec...

Extracts of many types of plants that are utilized as flavoring and seasoning agents in foods, have been used therapeutically for centuries. Sulphur compounds, terpenes and terpene derivatives, phenols, esters, aldehydes, alcohols and glycosides have shown antimicrobial and antioxidant functions. So far many literatures about the potential use of bioactive phytochemicals in food and pharmacy in...

ABSTRACT Introduction: Medicinal plants belong to Lamiaceae family are potential sources of new drugs to improve the treatment of diseases which its treatment is linked to anti-oxidative agents. In this paper, antioxidant potentials of some Lamiaceae species have been evaluated by two methods. Methods: phosphomolybdate assay for total antioxidant capacity and ferric reducing a...