BACKGROUND Certain HLA class II haplotypes have long been related with the risk of developing type 1 diabetes. The presence of the HLA haplotype DRB1*04/DQA1*03/DQB1*03:02, together with specific β-cell autoantibodies, contributes to the development and/or severity of insulin deficiency in type 1 diabetes. OBJECTIVE To evaluate the association of HLA risk haplotype HLA-DRB1/-DQA1/-DQB1 with β...

Many strains of a wide variety of bacterial species have been studied for their amino acid decarboxylase activity (Gale, 1946). However, to our knowledge the lactobacilli have not been examined. It has been shown in our laboratory that oral lactobacilli may be classified into three types according to their ability to attack certain carbohydrates, intensity of acid production from glucose, and b...

After the finding of 5-hydroxytryptamine (serotonin) in tissues (2), this laboratory reported that the amine is derived from the dietary amino acid, tryptophan (3), 5-hydroxytryptophan being the immediate precursor. Decarboxylation of 5-hydroxytryptophan was shown to be catalyzed by an enzyme found in many tissues and was originally considered to be distinct from 3,4-dihydroxyphenylalanine deca...

Amritotharanam Kashyam, a specific Ayurvedic drug, was the focus of current inquiry to evaluate its efficacy. For liver and digestive-related issues, this medication is suggested. This obtained from standard vendor in Chennai (India), GC-MS analysis carried out according procedure. A few critical biomolecules include benzoic acid, hexadecanoic 6,9-octadecadienoic 9-octadecenoic methyl ester (E)...

Abbreviations: ACC: 1-Amino-cyclopropane-1-carboxylic acid ADC: arginine decarboxylase AgNO3: silver nitrate AVG: aminoethoxyvinylglycine BA: 6-benzylaminopurine DFMA: α-DL-difluromethyl arginine DFMO: α-DL-difluromethyl ornithine IAA: indole acetic acid NAA: α-naphthalene acetic acid ODC: ornithine decarboxylase PA: polyamine Put: putrescine SAM: S-adenosyl-Lmethionine STS: silver thiosulphate...