Problem statement: Myocardial infarction is the combined result of environmental and personal factors. Data concerning the relation between anti-Phospholipid (aPL) antibodies and myocardial infarction in subjects without evidence of overt autoimmune disease are conflicting. Anticardiolipin antibody is detected in various diseases like rheumatoid arthritis, systemic lupus erythematosus and anti-...

OBJECTIVE To determine the association between the presence of anticardiolipin antibody (ACA) and history of recurrent spontaneous miscarriage. Also, to evaluate the association between raised ACA and activated partial thromboplastin time (APTT). METHODS This is a case-control study which was carried out in Basrah Hospital for Maternity and Children, Basrah, Iraq during January to September 2...

Several antibodies, including anticardiolipin antibodies (ACA), have been detected among chronically infected hepatitis C virus (HCV) patients. The present work aimed at ascertaining the clinical significance of ACA levels among HCV infection associated with two commonly encountered diseases, thrombocytopenia and arteriovenous-shunt malfunction. Six groups were studied, 11 HCV-positive thromboc...

The prevalence of anticardiolipin antibodies was evaluated in 70 children with juvenile chronic arthritis (JCA), in 25 adult patients with rheumatoid arthritis, in 42 healthy children and in 40 adult controls. Thirty seven (53%) patients with JCA were positive for IgG or IgM anticardiolipin antibodies, or both, and 30 (43%) for IgG anticardiolipin antibodies. In contrast, only seven (28%) adult...

The clinical course and serology of 16 cases of leptospirosis in an area with an unusually high endemic infection rate were studied to gain further insight into the pathology of the secondary immune phase that is typical of the disease. IgG anticardiolipin antibody concentrations were measured by immunoassay and found to be increased in eight serologically confirmed cases with severe complicate...

Background : Abortion is termination of pregnancy by any means before the fetus is sufficiently developed to survive on its own. The growing recognition that in this group of patients there may be an immunologic basis aroused interest in research workers. The anticardiolipin antibodies (aCL) which are commonly associated with recurrent pregnancy loss are lgG and lgM. lgM antibody is the largest...