BACKGROUND/AIMS This study was performed to investigate the cost effectiveness of Helicobacter pylori screening/eradication in South Korean patients treated with nonsteroidal anti-inflammatory drugs (NSAIDs) and/or aspirin. METHODS A decision Markov model was used to estimate the effectiveness and economic impact of an H. pylori screening/eradication strategy compared to a no-screening strate...

Long-term nonsteroidal anti-inflammatory drugs (NSAIDs) therapy has been associated with several adverse effects such as gastric ulceration and cardiovascular events. Among the molecular modifications strategies, the prodrug approach is a useful tool to discover new safe NSAIDs. The 1-(2,6-dichlorophenyl)indolin-2-one is a diclofenac prodrug which demonstrated relevant anti-inflammatory proper...

The majority of the "Australian COX-2-Specific Inhibitor (CSI) Prescribing Group" endorse the following points: CSIs are equivalent to non-steroidal anti-inflammatory drugs (NSAIDs) as anti-inflammatory agents. CSIs and NSAIDs modify symptoms but do not alter the course of musculoskeletal disease. CSIs do not eliminate the occurrence of ulcers or their serious complications, but are associated ...

and is difficult to remove. Dressings with the usual antiseptics can be applied for weeks without cure. I have found the following form of treatment, which is cheap, very satisfactory. The ulcer and the surrounding parts are cleaned with soap and warm water. The skin around the ulcer is smeared thickly with vaseline and then pure carbolic acid (phenol) is applied to the ulcer with a cotton swab...

The aim of the study was to study the anti-ulcer activity of the methanolic extract of the leaves of Capparis zeylanica Linn on experimental animal models. The methanol extract of Capparis zeylanica Linn. leaves was investigated for anti-ulcer activity against aspirin plus pylorus ligation induced gastric ulcer in rats. HCl-Ethanol induced ulcer in mice and indomethacin induced ulcer in rats at...

conclusions as a result of the full range uv-vis scanning of the responsible band in the hptlc experiments (200-700 nm), the flavonoid was the most imaginable natural compound. results through the bioassay guided fractionation method, the greatest antibacterial activities were related to the n-hexane extract. it was also revealed that the effective anti-mrsa agent of the assessed plant was a re...

background: the aim of this study was to compare the antibacterial efficacy of endemic satureja khuzistanica jamzad (skj) essential oil as root canal irrigation versus 2.5% sodium hypochlorite and 2% chlorhexidine gluconate.     methods: in current in vitro experimental study, fifty four single-rooted teeth were randomly divided into 6 groups of 9 samples: 2.5% sodium hypochlorite (naocl), 2% c...

background : prosthetic valve endocarditis (pve) is an important cause of morbidity and mortality associated with heart valve replacement surgery. the aim of the present study was to describe the early outcome of treatment in patients with pve in a single center. methods : the data of all the episodes of pve registered at our institution between 2002 and 2007 were collected and analyzed retrosp...

results analysis of the essential oil revealed the presence of pulegone (68.59%) piperitone (7.8%), piperitenone (7.8%), 1, 8-cineole (1.3%), and carvacrol (1.6%) as the major components. the results showed a significant activity against mdr a. baumannii with inhibition zones and minimal inhibitory concentration values in the ranges of 7-15 mm and 20-35 µl/ml respectively. conclusions this inve...