background : ascaridia galli , the largest nematode of small intestine of birds, especially the native poultry, may give rise to serious illness, pathological defects and economical losses even in modern poultry production systems. although various measures have been undertaken to vaccinate poultry against a.galli , no satisfactory results were obtained so far. however, there is no report on th...

background: to evaluate the immunological properties of leishmania major excreted- secreted (e-s) products on the progress of leishmaniasis in susceptible balb/c mice. methods: promastigotes of the leishmania major were cultured and e-s products were collected during the culture preiod. groups of balb/c mice (n= 12) were immunized with e-s products or whole antigen. animals were challenged with...

in the present study, pancreas glands in mehraban breed of female sheep were histomorphometricallystudied in four different age groups included: fetus, newborn, sexually mature and old ages. the results ofhistomorphometrical analysis with regard to frequency and percentage of parenchymal and stromal structures such as, exocrine secretory units, secretory ducts, blood vessels, islets of langerha...

Epithelial cells of human fetal intestines and of a colonic carcinoma cell line (HT-29) exhibited intracellular and surface binding of polymeric immunoglobulins of IgA and IgM classes; monomeric IgA and IgG did not bind to these cells. Secretory component was identified as the receptor involved in the immunoglobulin binding. This conclusion was confirmed by the following experiments: trypsin ab...

SEC15 function is required at a late stage of the yeast secretory pathway. Duplication of the gene encoding the ras-like, GTP-binding protein, Sec4, can suppress the partial loss of function resulting from the sec15-l mutation, but cannot suppress disruption of sec15. Analysis of the SEC15 gene predicts a hydrophilic protein product of 105 kD. Anti-Sec15 antibody recognizes a protein of 116-kD ...

Jaundiced babies undergoing phototherapy often develop diarrhoea. The cause of it is still uncertain. Increasing evidence supports a role of a secretory mechanism for the diarrhoea. We therefore studied the effects of bile from congenitally jaundiced rats undergoing phototherapy and of unconjugated bilirubin on rat small intestine in vivo and in vitro. Results suggest that: (1) the bile from ho...

Fasciolosis diagnosis, due to low sensitivity of coprological diagnostic method has been challenging for a long period. In this study, Dot-ELISA, one of the simplest and the most sensitive tests in this regard, was evaluated using excretory-secretory antigens of Fasciola hepatica to diagnose human fasciolosis Three groups consisting of patients infected with fasciolosis (n= 95), patients with o...

The herb Trianthema decandra. L (Aizoceae family) mentioned in Siddha Literatures had been studied in rats for its ability to inhibit gastric secretion and to protect the gastric mucosa against injuries caused by pyloric ligation, swim stress, acetic acid and cytodestructive agent ethanol. The extracts derived successively by using solvents of increasing polarity from the root powder of TD (Pet...

The Golgi apparatus is responsible for the genesis of secretory organelles of Toxoplasma gondii and lipid traffic to the vacuole. This study used anti-Golgi agents to demonstrate the importance of Golgi in Toxoplasma development. Monensin, Brefeldin A, Retinoic Acid and Okadaic Acid reduced the infection, leading to parasite elimination. Mon, BFA and RA affected secretory organelles and the Gol...