Lamson et al. (1-8) carried out extensive studies on the anthelmintic activity of a large number of alkylhydroxybenzenes and found that substances which apparently act through the cuticle of ascaris were ineffective when their melting points were too high. Harwood (9) demonstrated that if such chemicals were kept in the liquid phase by adulteration with certain organic liquids, their in vitro a...

In order to develop a better bioactive molecules with good efficacy, we synthesized a new series of Thiazolo [3,2-a] pyrimidine derivatives with good yield and studied their anthelmintic properties, structureactivity relationships (SARs). A new series of Thiazolo[3,2-a]pyrimidines have been synthesized through duff formylation, ‘One pot’ Biginelli reaction, cyclization followed by knoevenagel c...

Medicinal plants belongs to the oldest known health care products that have been used by mankind all over the world in the form of folklore medicines or traditional medicines or ethno medicines. The use of herbal drugs, extracts and their remedies have significantly increased throughout the world and the ‘green revolution’ in terms of herbal medicines has now achieved astonishing popularity. Th...

Tephrosia purpurea is a copiously branched herbaceous perennial plant distributed throughout the tropics which is used in the treatment of bronchitis, diuretic, pimples, tonic, laxative, cough, and tumour. The present study is an attempt to explore the anthelmintic activity of aqueous and methanolic extract of leaves of plant Tephrosia purpurea . The various concentrations of aqueous and methan...

The current study was carried out to test the root hair extract of Carex baccans, a traditionally used medicinal plant by the natives (Jaintia tribes) of Northeast India, for its anthelmintic efficacy on the trematode Artyfechinostomum sufrartyfex. The test parasites were exposed to different concentrations of the root hair extract of the plant and praziquantel, a broad-spectrum anthelmintic at...

Accepted on 9 December 2014 _____________________________________________________________________________ ABSTRACT The synthesis and characterization of new series of thiadiazepine derivatives of sultams have been presented. The structures were confirmed by elemental analysis, IR spectral,H NMR spectral data. All the compounds were screened for in vitro antimicrobial and anthelmintic activities...

AcanthospermumhispidumDC.is found in the tribal area of Koraput and Malkangiri districts andtraditionally used by the tribal people as anthelmintic, antidiabetic, antihypertensive, carminative and antifungal. No systematic study was conducted on A .hispidumDC. The present work was conducted to investigate the anthelmenticand Antidiabetic activities on the leaves of A.hispidumDC.Petrolium ether,...

Anthelmintic resistance creates a major hitch over the decades throughout the world. As per WHO only few drugs are frequently used in the treatment of helminth infestations in human beings. In view of this, an attempt has been made to study the anthelmintic activity of some newly synthesized 1-substituted imidazoles (1a-1d, 2a-2d) were synthesized and characterized by their spectral data. All t...

This study was conducted to evaluate the in vitro anthelmintic activity of the succinic acid (SA) isolated from sisal waste against gastrointestinal nematodes of goats, using the egg hatching and larvae motility assays. In addition, potential cytotoxicity of SA on Vero cell cultures was investigated by means of MTT (3-4,5-dimethylthiazol-2-yl, 2,5diphenyltetrazolium bromide) test. The SA induce...

Investigation of the traditional uses of Momordica charantia (Cucurbitaceae) in Togo (West Africa) showed that it is one of the most important local medicinal plants both for ritual and ethnomedical practices. There was a high degree of consensus (>50%) for use in the treatment of gastrointestinal and viral disease among 47 groups of village informants in the general population, while 19 tradit...