2NP is among the priority pollutants for environmental ecosystem and poses a threat to health of living things by mixing in wastewater. Therefore, determination important. In this study, glassy carbon (GC) electrode surface was modified with 1-amino-2-naphthol-4-sulfonic acid (ANSA). The electrochemical behavior voltammetric 2-nitrophenol (2NP) on (ANSA-GC) performed. Firstly, it decided that s...

Two convergent total syntheses of the ansa-polyketide (-)-kendomycin (1) are described. The syntheses benefit from the use of readily available and cheap starting materials. Highly complex diastereoselective Claisen-Ireland rearrangements were used to introduce the (E)-double bond and the C16-Me group. The ring closure of the strained ansa macrocycle was achieved by ring-closing metathesis and ...

Bacterial L-asparaginase has been a universal component of therapies for childhood acute lymphoblastic leukemia since the 1970s. Two principal enzymes derived from Escherichia coli and Erwinia chrysanthemi are the only options clinically approved to date. We recently reported a study of recombinant L-asparaginase (AnsA) from Rhizobium etli and described an increasing type of AnsA family members...

Neuropeptide Y and norepinephrine are localized in sympathetic nerve terminals throughout the heart. We sought to determine the functional distribution of the neuropeptide Y-containing sympathetic fibers to the sinus and atrioventricular (AV) nodal regions. We recorded cycle length, AV interval, and arterial pressure in 14 anesthetized dogs. We assessed the release of neuropeptide Y from sympat...

Expression of the two Bacillus subtilis genes encoding L-asparaginase is controlled by independent regulatory factors. The ansZ gene (formerly yccC) was shown by mutational analysis to encode a functional L-asparaginase, the expression of which is activated during nitrogen-limited growth by the TnrA transcription factor. Gel mobility shift and DNase I footprinting experiments indicate that TnrA...

In this study, we investigated the chemical functionalization of carboxylated multiwalled carbon nanotubes (MWCNT–COOH) by 1-Amino-2-naphthol-4-sulfonic acid (ANSA). The functionalized MWCNTs exhibited good aqueous solubility due to the presence of the –OH and – SO3H groups of ANSA. The antimicrobial activity of the MWCNT–COOH as well as its functionalized multiwall nanotube MWCNT-CO-2-(1-amino...

(2)] The first examples of uncharged aryl substituted fluorinated hydridophosphazenes, N3P3F4(Ar)H [Ar — C6H5 (1), pwere obtained in an unprecedented manner upon fluorination of diaryloctachlorobi(cyclophosphazenes) ðN6P6Cl8ðArÞ2Þ [Ar — C6H5, p-ClC6H4] using KF in acetonitrile. The compounds (1) and (2) were stable to air and moisture, and were characterized by spectral and analytical methods. ...