نتایج جستجو برای: angiotensinogen m235t polymorphism

تعداد نتایج: 109322  

Journal: :Hypertension 2000
A S Wierzbicki M Lambert-Hammill P J Lumb M A Crook

The role of renin-angiotensin system polymorphisms as risk factors for coronary heart disease (CHD) is controversial. This study investigated their role in patients with heterozygous familial hypercholesterolemia (FH). Polymorphism frequencies for angiotensin-I-converting enzyme insertion/deletion (ACE I/D), angiotensinogen M235T, and angiotensin-II type I receptor (AG2R) A1166C were determined...

2017
Min Zhu Minjun Yang Jiangbo Lin Huanhuan Zhu Yifei Lu Bing Wang Yinshen Xue Congfeng Fang Lijiang Tang Baohui Xu Jianjun Jiang Xiaofeng Chen

BACKGROUND AND OBJECTIVE Percutaneous coronary intervention, despite being effective for coronary revascularization, causes in-stent restenosis due to neointimal hyperplasia in a large number of patients. The renin-angiotensin system is involved in neointimal hyperplasia. This study sought to evaluate seven gene polymorphisms of key renin-angiotensin system components, including angiotensinogen...

2014
Zohreh Rahimi Mahmoudreza Moradi Hamid Nasri

BACKGROUND The renin angiotensin aldosterone system (RAAS) plays a vital role in regulating glucose metabolism and blood pressure, electrolyte and fluid homeostasis. The aim of this systematic review is to assess the association of the RAAS genes with diabetes mellitus (DM) and its complications of retinopathy, neuropathy and cardiovascular disease (CVD). MATERIALS AND METHODS The relevant En...

Journal: :Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2004
Torsten Slowinski Petra Diehr Patrick Kleemann Lutz Fritsche Lutz Renders Klemens Budde Ingeborg A Hauser Hans H Neumayer Berthold Hocher

BACKGROUND Genes determining the activity of the renin-angiotensin system (RAS) may be alloantigen-independent factors influencing kidney allograft function. We determined if gene polymorphisms of the RAS are associated with early and long-term post-transplantation graft dysfunction in 405 Caucasian kidney recipients with graft survivals of >2 years. METHODS We calculated the slopes of serum ...

Journal: :Hypertension 2003
Natapong Kosachunhanun Steven C Hunt Paul N Hopkins Roger R Williams Xavier Jeunemaitre Pierre Corvol Claudio Ferri Richard M Mortensen Norman K Hollenberg Gordon H Williams

We sought to determine whether genes of the renin-angiotensin-aldosterone system can predict the nonmodulating intermediate phenotype in essential hypertension. Aldosterone responses to angiotensin II were assessed in 298 subjects with hypertension. Subjects were genotyped at the angiotensinogen M235T, angiotensin-converting enzyme I/D, aldosterone synthase C-344 T, renin, angiotensin II type 1...

Journal: :Clinical science 2002
Sabine Hertwig Henry Völzke Daniel M Robinson Wolfgang Motz Rainer Rettig

The present study was designed to prospectively test the hypothesis that gene polymorphisms of the renin-angiotensin system are associated with recurrent restenosis after repeated percutaneous transluminal coronary angioplasty. Five hundred and eleven patients after first successful angioplasty were characterized with respect to the angiotensinogen M235T, angiotensin-converting enzyme insertion...

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