Hydrogen sulfide (H(2)S) depresses mitochondrial function and thereby metabolic rates in mice, purportedly resulting in a state of "suspended animation." Volatile anesthetics also depress mitochondrial function, an effect that may contribute to their anesthetic properties. In this study, we ask whether H(2)S has general anesthetic properties, and by extension, whether mitochondrial effects unde...

a general, simple, practical and convenient method has been described for the synthesis of anesthetic drug thiopental using thiourea in the presence of sodium ethoxide. anesthetic drug of thiopental was prepared in two stages; during the first stage, the alkylation of mthyl cyanoacetate was performed which was then to be followed by cyclization. alkylation of methyl cyanoacetate which was perfo...

Chronic, low-level exposure to waste anesthetic gases has been linked to increased incidences of neurologic and reproductive dysfunction, hepatic and renal toxicity, and neoplasia in humans. We have shown previously that one brand of activated charcoal canister (F/Air) used for passive scavenging of halogenated gases does not completely remove isoflurane during anesthetic protocols used in conv...

context lumbar central spinal stenosis is common and often results in chronic persistent pain and disability, which can lead to multiple interventions. after the failure of conservative treatment, either surgical or nonsurgical modalities such as epidural injections are contemplated in the management of lumbar spinal stenosis. evidence acquisition recent randomized trials, systematic reviews an...

Introduction: Staffs of operating room are continuously exposed to anesthetic gases and                                                       ionizing radiation. Adaptive response, as a defense mechanism, will occur when cells become exposed to a low dose of factors harming DNA that causes in the next exposures to higher doses o...

background: severe abdominal pain is not common after laparoscopic surgeries, but acute or chronic pain after operation is considerable in some patients. post-operative pain control after laparoscopic surgeries, is conventionally achieved using analgesics such as non-steroidal anti-inflammatory drugs (nsaids) and narcotics, but their administration has a lot of side effects. this study compares...