BACKGROUND It has been reported that some alopecia areata patients have zinc deficiency. There have also been several reports published concerning oral zinc sulfate therapy, with encouraging results, in some alopecia areata patients. OBJECTIVE The purpose of this study was to evaluate the therapeutic effects of oral zinc supplementation for twelve weeks in alopecia areata patients who had a l...

BACKGROUND Central centrifugal cicatricial alopecia (CCCA) is the most common cause of scarring alopecia among women of African descent which affects the central scalp and spreads centrifugally but spares the lateral and posterior scalp. OBJECTIVES The objective of this study is to report on a new clinical variety of CCCA presenting with patchy alopecia involving the lateral and posterior sca...

BACKGROUND To precisely calculate skin dose and thus to evaluate the relationship between the skin dose and permanent alopecia for pediatric medulloblastoma patients treated with proton beams. METHODS The dosimetry and alopecia outcomes of 12 children with medulloblastoma (ages 4-15 years) comprise the study cohort. Permanent alopecia was assessed and graded after completion of the entire the...

IMPORTANCE Nilotinib, a recently approved multitargeted tyrosine kinase inhibitor targeting the BCR-Abl translocation involved in chronic myelogenous leukemia, reportedly produces alopecia according to the package insert, but clinical and histologic descriptions of the alopecia are lacking. OBSERVATIONS A 33-year-old woman with chronic myelogenous leukemia developed widespread alopecia involv...

Alopecia areata occurs more often in Down's syndrome than would be expected by chance, sixty cases being found among 1000 patients with this syndrome compared with one case among 1000 subnormal controls. Because alopecia areata is associated with some organ-specific autoimmune disease and thyroid antibodies are often found in Down's syndrome sera from affected patients were examined for the p...

1. Christophers E, Mrowietz U. Psoriasis. In: Freedberg IM, Eisen AZ, Wolff K, Austen KF, Goldsmith LA, Katz SI, editors. Fitzpatrick’s dermatology in general medicine. 6th ed. New York: Mc-Graw Hill; 2003. p. 407-27. 2. Runne U, Kroneisen-Wiersma P. Psoriatic alopecia: Acute and chronic hair loss in 47 patients with scalp psoriasis. Dermatology 1992;185:82-7. 3. Shuster S. Psoriatic alopecia. ...

Alectinib, a novel alternative anaplastic lymphoma kinase (ALK) inhibitor, is highly effective against ALK-positive non-small cell lung cancer (NSCLC) and is well tolerated. Molecular targeted agents generally have little contribution to alopecia. We encountered a case of alopecia that developed gradually over 2 months after initiation of alectinib administration for the treatment of ALK-positi...

Alopecia areata (AA) is a recurrent, non-scarring type of hair loss affecting the hair follicles and sometimes the nails. Current evidence indicates that hair follicle inflammation in alopecia areata is caused by a T-cell mediated autoimmune mechanism occurring in genetically predisposed individuals. Environmental factors like infections, diet, vaccination and stress may be responsible for trig...

Alopecia areata and vitiligo are autoimmune diseases, both associated with multiple autoimmune comorbidities. Many studies show colocalization of these diseases at the same anatomical site. Here, we have a case where both disorders were reported to present in the same patient. Diphenylcyclopropenone (diphencyprone, DCP) is used in the treatment of alopecia areata and may induce vitiligo in some...

Background & Aims: Alopecia areata is a chronic inflammatory disorder that affects the hair follicles. The condition most commonly presents with the sudden appearance of non-scarring discrete patches of alopecia on the scalp. Due to being an autoimmune disease, alopecia areata is observed in concomitantly with other diseases. In some studies, ocular alterations were surveyed in these patients. ...