The placebo effect is a neurobiological and psychophysiological process known to influence perceived pain relief. Optimization of placebo analgesia may contribute to the clinical efficacy and effectiveness of medication for acute and chronic pain management. We know that the placebo effect operates through two main mechanisms, expectations and learning, which is also influenced by sleep. Moreov...

Placebo analgesia is one of the most robust and best-studied placebo effects. Recent researches suggest that placebo analgesia activated the μ-opioid receptor signalling in the human brain. However, whether other opioid receptors are involved in the placebo analgesia remains unclear. We have previously evoked placebo responses in mice (Guo et al. 2010, 2011) and these mice may serve as a model ...

: 112 Transcutaneous carbon dioxide measurements and maternal pain scores in laboring parturients Presenting Author: Paloma Toledo M.D. Presenting Author's Institution: Northwestern University, Feinberg School of Medicine Chicago, IL Co-Authors: Renee C. Gora B.S.N. Northwestern University, Feinberg School of Medicine Chicago, IL Mary Jane Ebarvia B.S.N. Northwestern University, Feinberg School...

Abstract Aim We objectively re-assessed prescribing of analgesia for surgical admissions at Watford General Hospital, in accordance with Trust Guidelines Method Total 117 Patients. collected data prospectively the 1st Cycle 21/09/2021 – 04/10/2021 and 2nd 04/01/2022 17/01/2022. Intervention was through virtual poster daily reminders to on-call team Results & Conclusions When patients were p...

objectives: aim of the present work was to investigate the anti-inflammatory, analgesic and antiulcer effects of red seaweed porphyra vietnamensis (p. vietnamenis). materials and methods: aqueous (por) and alcoholic (pe) fractions were successfully isolated from p. vietnamenis. further biological investigations were performed using a classic test of paw edema induced by carrageenan, writhing in...

BACKGROUND Caudal analgesia is commonly employed to provide excellent intra- and postoperative analgesia for primary hypospadias repair in children. Several additives to local anesthetics are commonly employed to increase the block duration, although these have uncertain benefits. OBJECTIVES This study investigated whether, in caudal analgesia with levobupivacaine 0.25%, the addition of S (+)...

OBJECTIVES To evaluate patient attitudes about epidural services in labour and correlate them with patient options and actual usage of epidural analgesia. DESIGN Questionnaire survey. SETTING Eight Hospital Authority obstetrics units. PARTICIPANTS A cohort of new antenatal patients and a cohort of postnatal in-patients over 1 calendar month. MAIN OUTCOME MEASURES Antenatal patient aware...

Labor pain is one of the most severe pains. Labor is a complex and individual process with varying maternal requesting analgesia. Labor analgesia must be safe and accompanied by minimal amount of unwanted consequences for both the mother and the child, as well as for the delivery procedure. Epidural analgesia is the treatment that best meets these demands. According to the American Congress of ...

background gabapentin is an anticonvulsant that has postoperative analgesic effects but there are limited studies on its postoperative administration. objectives the present study was conducted to evaluate the effect of the postoperative oral gabapentin on pain and morphine consumption. patients and methods in a double blind, randomized study, 64 patients undergoing internal fixation of tibia u...

background: intrauterine device (iud) is an effective and long term method of contraception that can be used without continued effort by the user to prevent pregnancy perfectly. pain during iud insertion is one of the obstacles to properly using the device. thus, using different methods of analgesia and anesthesia to alleviate this pain has been studied by many researchers. this review article ...