ABT-773 was tested against 317 fastidious isolates; it inhibited 99% of organisms at a concentration of 4.0 microg/ml. With ampicillin-sulbactam and levofloxacin, only 2 and 6% of these strains, respectively, were resistant at the breakpoint. With clindamycin, penicillin G, and metronidazole, 22, 26, and 58% of the strains, respectively, were resistant.

Garenoxacin (BMS 284756) was active against 105 of 108 (97%) recent clinical Gardnerella vaginalis isolates at < or =2 micro g/ml by using the reference agar dilution method for anaerobes. Twenty-eight percent of isolates (31 of 108) were resistant to metronidazole, and 44% were resistant to doxycycline. All were susceptible to clindamycin and ampicillin-sulbactam.

Yersinia enterocolitica serotype 0:5,27 biotype 2 was isolated from the intestinal contents of a common garter snake (Thamnophis sirtalis). The isolate possessed virulence associated phenotypes in all tests conducted. It was susceptible to amikacin, ampicillin/sulbactam, aztreonam, cefoperazone, cefotaxime, ceftazidime, ceftriaxone, cefuroxime, ciprofloxacin, gentamicin, imipenem, mezlocillin, ...

We describe a case of vertebral osteomyelitis caused by Prevotella intermedia, which is an extremely unusual cause of vertebral osteomyelitis. The organism was isolated from vertebral biopsies and the patient was treated successfully with intravenous ampicillin-sulbactam and clindamycin. Diagnosis and management of this condition are described, and the importance of anaerobic bacteria in the pa...

From the PG Department of Pharmacology & *Department of Surgery, Govt. Medical College, Srinagar (Kashmir) J&K-India Correspondence to : Dr Vishal R. Tandon, Consultant/Lecturer-Pharmacology 5/B, Near Arya Samaj Bakshinagar Jammu-J&K-India 1800001 Prospective Randomized Open Labeled Study Comparing Prophylactic Efficacy of Parenteral Single Dose Cefuroxime vs Ampicillin-Sulbactam in Patients un...

A six-year-old male patient with no known history of disease was presented due to an unfamiliar Streptococcus constellatus growth that developed alongside a tooth abscess and fistulized. The admitted redness, swelling, tenderness in the left-most section his face. We learned visited dentist three weeks prior complaints swelling jaw decay. had leukocyte count 22,600/μL (neutrophil: 17,190/μL), C...

The aims of this study were to investigate drug resistance rates, types of extended spectrum beta lactamases (ESBLs), and molecular epidemiological characteristics of 43 Shigella sonnei isolates. Ampicillin-sulbactam, amoxicillin-clavulanate, chloramphenicol, and ciprofloxacin were the most active antibiotics. Five isolates harbored bla SHV-12, bla(TEM-1) and bla(CTX-M-15). More than 90% of the...