نتایج جستجو برای: aml m7
تعداد نتایج: 13547 فیلتر نتایج به سال:
Metallothionein, a two-domain protein, naturally binds seven gram atoms of divalent ions such as Zn and Cd. Four of the metals (M1, M5, M6 and M7) are found in the alpha-domain and three (M2, M3 and M4) in the beta-domain. Previous studies have shown that metals in the beta-domain are more readily exchangeable, and the level of avidity is site specific. By semi-empirical MNDO modified neglect o...
To draw the cytogenetic profile of childhood and adult acute megakaryoblastic leukemia (M7), the Groupe Français de Cytogénétique Hématologique collected 53 cases of M7 (30 children and 23 adults). Compared to other acute myeloid leukemias, M7 is characterized by a higher incidence of abnormalities, a higher complexity of karyotypes, and a different distribution of abnormalities among children ...
Canagliflozin is an oral antihyperglycemic agent used for the treatment of type 2 diabetes mellitus. It blocks the reabsorption of glucose in the proximal renal tubule by inhibiting the sodium-glucose cotransporter 2. This article describes the in vivo biotransformation and disposition of canagliflozin after a single oral dose of [(14)C]canagliflozin to intact and bile duct-cannulated (BDC) mic...
We find the gravity duals to an infinite series of N = 3 Chern–Simons quiver theories. They are AdS4 ×M7 vacua of M–theory, with M7 in a certain class of 3–Sasaki–Einstein manifolds obtained by a quotient construction. The field theories can be engineered from a brane configuration; their geometry is summarized by a “hyperKähler toric fan” that can be read off easily from the relative angles of...
We find the gravity duals to an infinite series of N = 3 Chern-Simons quiver theories. They are AdS4 ×M7 vacua of M-theory, with M7 in a certain class of 3-SasakiEinstein manifolds obtained by a quotient construction. The field theories can be engineered from a brane configuration; their geometry is summarized by a “hyperKähler toric fan” that can be read off easily from the relative angles of ...
acute myeloid leukemia (aml) is a type of poor prognosis hematological malignancies characterized by heterogeneous clonal expansion of myeloid progenitors. leukemic stem cells are thought to form the majority of a cell population in minimal residual diseases (mrds) which are resistant to current chemotherapeutic regimens and mediate disease relapse. current therapeutic vaccine strategies have d...
In this note we consider the existence problem for symplectic 3forms of G2-type or G̃2-type on 7-manifolds. We find a first example of a closed G̃2-structure on S 3 × S4. We also prove that any integral symplectic 3-forms on a compact 7-manifold M7 can be obtained by embedding M7 to a universal space (W 3(80+8.C 3 8 ), h). MSC: 53C10, 53C42
Cloned hybridoma cell lines were obtained from fusions of murine myeloma cells with lymphocytes of mice immunized against human breast cancer cells. Hybridomas F36/22 and M7/ 105 produced antibodies whose binding to breast cancer cells could not be inhibited by prior absorptions with fibroblasts, lymphoblastoid cells, or erythrocytes. Results from cell surface binding assays using a panel of tu...
Anti-idiotypic monoclonal antibodies (MoAbs) were prepared in a syngeneic system against anti-carcinoembryonic antigen (CEA) MoAb 5B3 (IgG1), which reacted with a carbohydrate moiety on CEA, and MoAb MA208 (IgG1), which reacted with a peptide on CEA. Anti-idiotypic MoAb T3-503 and T4-202 recognized the private idiotype of MoAb 5B3; anti-idiotypic MoAb M7-049 and M7-625 did so for MoAb MA208. Id...
Canagliflozin is an oral antihyperglycemic agent used for the treatment of type 2 diabetes mellitus. It blocks the reabsorption of glucose in the proximal renal tubule by inhibiting the sodium-glucose cotransporter 2. This article describes the in vivo biotransformation and disposition of canagliflozin after a single oral dose of [C]canagliflozin to intact and bile duct-cannulated (BDC) mice an...
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