Voges & Proskauer [1898] observed that when strong alkali was added to broth cultures of certain species of bacteria there developed, after an interval of time, a pink colour. Subsequently the work of Harden [1906] and of Harden & Norris [1911] established that the chemical reaction responsible was one between diacetyl and creatine (or certain similar substances). Attempts to make the reaction ...

In the title compound, C(17)H(13)BrClNO, the dihedral angle between the naphthol ring system and the chloro-benzene ring is 76.59 (11)°. This twisted conformation is supported by an intra-molecular O-H⋯N hydrogen bond. In the crystal, [100] chains arise, with adjacent mol-ecules linked by an N-H⋯O hydrogen bond, a C-H⋯π inter-action and an aromatic π-π stacking contact [centroid-to-centroid sep...

Herein, a direct C8-oxygenation of naphthalene derivatives is described. Different carbonyl groups were used as directing group to deliver corresponding naphthols via palladium-catalyzed oxidation reaction using PhI(OAc)2 in TFA/TFAA mixture. Interestingly, when Weinreb amide was employed the group, naphtholactone skeleton directly obtained. This methodology applied synthesis variously substitu...

In the title compound, C(23)H(25)NO, an intra-molecular O-H⋯N hydrogen bond defines the mol-ecular conformation; the naphthol mean plane and the benzene ring form a dihedral angle of 75.8 (2)°. The piperidine ring adopts a chair conformation. The crystal packing exhibits no short inter-molecular contacts.

To assess the potential use of O-H stretching modes of aromatic alcohols as ultrafast local probes of transient structures and photoacidity, we analyze the response of the O-H stretching mode in the 2-naphthol-acetonitrile (2N-CH3CN) 1:1 complex after UV photoexcitation. We combine femtosecond UV-infrared pump-probe spectroscopy and a theoretical treatment of vibrational solvatochromic effects ...

Fluorescence probes based on excited state proton transfer (ESPT) have been recently developed for microheterogeneous media. The ESPT behaviour of a series of substituted naphthols (4-chl oro-1-naphthol, 5-amino-1-naphthol , 4-methoxy1-naphthol, 7-methoxy-2-naphthol , 3-amino-2-naphthol, 6-bromo-2naphthol and 1-bromo-2-naphthol) is investigated in liposomes, using steady state and time resolved...

A simple and sensitive method for the determination of carbaryl in whole blood and commercial formulations, based on normal, and synchronous firstand second-derivative fluorescence spectra, is presented. Solvent effects on the spectral characteristics of carbaryl solutions and the influences of instrumental parameters are described in detail. Two methods have been developed, with neutral (for c...

Excited-state proton transfer from 5,8-dicyano-2-naphthol to methanol takes place in CO2/methanol mixtures, in the pressure and temperature ranges of supercritical CO2. The efficiency of the proton-transfer step decreases with the pressure. This is assigned to the perturbation of the methanol clusters solvating the naphthol.