To characterize the rate and regulation of alveolar fluid clearance in the uninjured human lung, pulmonary edema fluid and plasma were sampled within the first 4 h after tracheal intubation in 65 mechanically ventilated patients with severe hydrostatic pulmonary edema. Alveolar fluid clearance was calculated from the change in pulmonary edema fluid protein concentration over time. Overall, 75% ...

Little is known about the relative importance of monocyte and tissue-resident macrophages in the development of lung fibrosis. We show that specific genetic deletion of monocyte-derived alveolar macrophages after their recruitment to the lung ameliorated lung fibrosis, whereas tissue-resident alveolar macrophages did not contribute to fibrosis. Using transcriptomic profiling of flow-sorted cell...

background and aim: the inferior alveolar canal must be constantly examined as an important anatomical landmark in the study of lower jaw, particularly posterior body and mandibular ramus sites, in dental and surgical procedures. in the present study, the effect of two pathological lesions, ameloblastomas and keratocystic odontogenic tumour, on canal displacement were investigated. materials an...

conclusions patients treated with ptu should be closely monitored and followed up, even if the drug has been used for several years. when patients develop progressive dyspnea with alveolar opacities on chest imaging that cannot be explained otherwise, alveolar hemorrhage should be an important differential diagnosis while investigating the case. early diagnosis and prompt discontinuation of the...

the role of alveolar macrophages in the production of granulocyte/ macrophage colony-stimulating factor(s) by the rat lung was investigated. lavaged lungs, when incubated at proper weight per volume of culture medium, produced the same amount of colony-stimulating factor as unlavaged ones. both lavaged and unlavaged lungs produced similar types of colony-stimulating factor (s). prolonged incuba...

Alveolar bone loss is a characteristic of the development periodontitis; its prevention major clinical challenge in treatment periodontal disease. can significantly affect patient's quality life. In addressing chal-lenges recovering alveolar loss, fucoidan has attracted attention as potential material due to numerous biological activities, one which regulate osteogenic cell function so facilita...

Secondary bone grafting in the alveolar cleft is performed to improve alveolar shape, guide permanent tooth eruption or move permanent teeth in the alveolar cleft area, and improve a concaved base in the nasal wing [1]. Such bone grafting is typically conducted 6-9 years before canine tooth eruption [2]. However, in some cases, patients obtain their permanent dentition without receiving bone gr...

The uptake of different surfactant lipids-dipalmitoylphosphatidylcholine (DPPC), phosphatidylglycerol (PG), or phosphatidylinositol (PI)-and liposomes with a surfactant-like composition by alveolar type II cells (alveolar type II cells) and macrophages (alveolar macrophages) was studied in vitro. Fluorescent-labeled liposomes containing either 86% of the studied lipid, i.e., DPPC, PG, PI, and 6...

background: localized alveolar ridge defect may create physiological and pathological problems. developments in surgical techniques have made it simpler to change the confi guration of a ridge to create a more aesthetic and more easily cleansable shape. the purpose of this study was to compare the effi cacy of alveolar ridge augmentation using a subepithelial connective tissue graft in pouch an...

Lung diseases characterized by alveolar damage such as bronchopulmonary dysplasia (BPD) in premature infants and emphysema lack efficient treatments. Understanding the mechanisms contributing to normal and impaired alveolar growth and repair may identify new therapeutic targets for these lung diseases. Axonal guidance cues are molecules that guide the outgrowth of axons. Amongst these axonal gu...