A fibropapilomatose (FP) é uma doença multifatorial, neoplásica e infecciosa que afeta todas as espécies de tartarugas marinhas, o Chelonid alphaherpesvirus 5(ChHV5) tem sido apontado como agente etiológico primário. Essa caracterizada por tumores cutâneos, mas fibromas viscerais, mixofibromas fibrossarcomas também têm relatados podem interferir nas funções sistêmicas. Apesar descrições anterio...

Actin filaments, microtubules and intermediate filaments form the cytoskeleton of vertebrate cells. Involved in maintaining cell integrity and structure, facilitating cargo and vesicle transport, remodelling surface structures and motility, the cytoskeleton is necessary for the successful life of a cell. Because of the broad range of functions these filaments are involved in, they are common ta...

BACKGROUND Equine herpesvirus type 1 (EHV-1), a member of the Alphaherpesvirinae, is spread via nasal secretions and causes respiratory disease, neurological disorders and abortions. The virus is a significant equine pathogen, but current EHV-1 vaccines are only partially protective and effective metaphylactic and therapeutic agents are not available. Small interfering RNAs (siRNA's), delivered...