The high molecular weight melanoma-associated antigen (HMW-MAA) is a membrane-bound chondroitin sulphate proteoglycan that is highly expressed on the surface of melanoma cells. It represents an attractive target for immunotherapy of malignant melanoma. Previously, it was reported that HMW-MAA was detected in about 20-30% of primary acral lentiginous melanoma (ALM) lesions by immunohistochemical...

Certain characterization properties of time-varying periodic Poisson flows are studied in terms of almost-lack-of-memory (ALM) distributions. Parameter estimation formulas are derived. A method for verifying the hypothesis on the membership of a sample to the class of ALM-distributions is developed. Algorithms for computing critical levels and power of the likelihood ratio test by the Monte Car...

BACKGROUND Dietary surveys suggest that many older, community-dwelling adults consume insufficient dietary protein, which may contribute to the age-related loss of lean mass (LM). OBJECTIVE The objective of the study was to determine the association between dietary protein and changes in total LM and nonbone appendicular LM (aLM) in older, community-dwelling men and women. DESIGN Dietary pr...

BACKGROUND Age-related progressive loss of muscle mass is an increasing problem in our aging society, affecting physical ability, risk of falls, and need for health care. Telomere length has been recognized as a marker of biological age on the population level. The relation between muscle mass in advanced age and telomere length, however, has rarely been examined. OBJECTIVE We evaluated the r...

Understanding the Mobile Environment ................................................................................................... 3 Mobile is Fragmented ....................................................................................................................... 3 Mobile is Dynamic ....................................................................................................

Application Layer Multicast (ALM) is an attractive solution to overcome the deployment problems of IP-Multicast. We show how to cope with the challenges of incorporating wireless devices into ALM protocols. As a first approach we extend the NICE protocol, significantly increasing its performance in scenarios with many devices connected through wireless LAN.

Additive Layer Manufacturing (ALM), also broadly known as 3D printing, is a new technology to produce 3D objects. As an opposite approach to the conventional subtractive manufacturing process, 3D objects are created by adding thin material layers over layers. Until recently, they have been used, mainly, for plastic models. However, the technology has evolved making it possible to use high-quali...

the goal of this study was to prepare and characterize alginate microspheres as an antigen delivery system and adjuvant for immunization against leishmaniasis. microspheres encapsulated with autoclaved leishmania major (alm) and quillaja saponin (qs) were prepared by an emulsification technique and characterized for size, encapsulation efficiency and release profile of encapsulates. selection o...

Application Layer Multicast (ALM) is an alternative to IP multicast, which has yet to achieve a widespread deployment in the Internet. ALM places multicast primitives directly in the multicast members, i.e. end systems, which use an overlay topology on top of the physical network for multicasting. The overlay consists of unicast connections between the members, hence bypasses the need for multi...