BACKGROUND Children with atopic eczema in infancy often develop allergic rhinoconjunctivitis and asthma, but the term "atopic march" has been questioned as the relations between atopic disorders seem more complicated than one condition progressing into another. OBJECTIVE In this prospective multicenter study we followed children with eczema from infancy to the age of 10 years focusing on sens...

until now, there have been various studies concerning bottle-fed and breast-fed children. prevalence of allergic manifestations like eczema and asthma among bottle-fed children is much higher than healthy controls. in this study, we found that respiratory infection for breast-fed children was 3.1%, whereas in bottle-fed children it was 25.1%for gut disorders, 9.2% in breast-fed vs.13.1 % for bo...

this study was conducted to examine if allergic contact dermatitis (acd) alters the expression of mmps in human dermal fibroblasts. fibroblasts are the primary source for mmp and matrix production in skin. mmps are known to involve in a number of physiological and pathological processes. some published data indicated a gelatinase-like activity in acute and chronic phases of allergic contact der...

Background: Job-related allergic contact dermatitis (ACD) mayprolong the disease duration, increase disabilities, and decreasethe patient’s quality of life. The aim of this study was to determinecommon allergens causing ACD, investigating certain featuresof the disease and evaluating its relation to the patients’ jobs.Method: In this cross-sectional study, relevant data was obtainedfrom patch t...

Extending the classical concept considering an imbalance exclusively of T helper(h) 1 and Th2 cells on the bottom of many inflammatory diseases, Th17 cells were recently described. Today, there is sufficient experimental evidence to classify psoriasis and allergic contact dermatitis (ACD) amongst other inflammatory skin disorders as IL-17 associated diseases. In several human studies, T-cell-cl...

INTRODUCTION Clinical studies indicate that contact allergy to glucocorticosteroids (GCS) is not rare and has been increasingly reported over the past decade. Among the risk factors for developing contact hypersensitivity to topical corticosteroids, chronic inflammatory skin diseases and polyvalent contact allergy seem to be most important. AIM To present the structure of contact allergy in t...

Results At the age 20 years, atopic eczema was equally common despite of atopic heredity. Allergic rhinitis was significantly (p=0.004) more common in children prone to atopy. Atopic eczema at age 2, 7 and 18 years flagged atopic eczema lasting until young adulthood, and predicted later rhino conjunctivitis (60%) and asthma at age 20y (28%). Timothy grass (65%) and birch pollen (55%) sensitizat...

Protein contact dermatitis is a skin condition not well known and underdiagnosed by dermatologists, resulting from an IgE-mediated allergic reaction. Clinically it presents as a chronic hand and/or forearms eczema of occupational origin, especially in professionals who work as food handlers. Epicutaneous tests are negative, and to diagnose this condition it is necessary to perform immediate-typ...

asthma and allergic diseases present a major health burden. information on the prevalence of these diseases indicates that these diseases are increasing in various parts of the world. it was hoped that this study would be helpful to health system policy-makers in planning allergy prevention programs in the region.the prevalence of asthma and allergic diseases and relation between the various ri...

In our previously study, we demonstrated an association between eczema and the risk of glioma. Our results revealed that eczema significantly reduced the risk of glioma. Here, we review related published data to investigate the association between allergic diseases and the risk of cancer. We also discuss the potential mechanism of how allergic diseases might modify the risk of cancer.