First described in 1951 as an allergic and granulomatous angiitis, Churg-Strauss syndrome (CSS) is a small-vessel vasculitis. Mean age at the time of diagnosis is approximately 50 years, with a sex ratio around 1. Asthma is the central feature of CSS and precedes the systemic manifestations in almost all cases, whereas 70% of the patients have maxillary sinusitis, allergic rhinitis, and/or sinu...

A 43-year-old man, who died five months after the onset of left-sided sensory deficit, had angiographical and pathological evidence of an angiitis confined largely to the distribution of the right middle cerebral artery. Histological examination identified this process to be intracranial noninfectious granulomatous angiitis. Although certain clinical and pathological features of this disorder o...

the aim of current study is to describe clinical similarities and differences between atopic and non-atopic asthma in children. in a cross-sectional study, 95 asthmatic children (75 allergics and 20 nonallergics) were included in the study. demographic, clinical, and familial history were compared between two groups. there was no significant differences between variables like sex, age of onset ...

Almost all pathological diagnoses made from a native kidney biopsy come from careful examination of the renal cortex. In fact, a good biopsy specimen contains little medulla. It is important, to remember, however, that certain diseases have a characteristic medullary component. Medullary angiitis has histological features of interstitial hemorrhage in the medulla with an associated polymorphonu...

BACKGROUND Vascular damage in the central hand knob area can mimic peripheral motor nerve deficits. CASE PRESENTATION We describe the case of a woman presenting with apparent peripheral neuropathy. Brain magnetic resonance imaging and computed tomography angiography revealed an infarct in the precentral hand knob area, with significant stenosis in the right proximal middle cerebral artery tru...

Purpose: We report a case of bilateral frosted branch angiitis caused by anti-phospholipid antibody syndrome.Case summary: A 60-year-old female complained worsening vitreous floaters and decreased visual acuity in both eyes. The initial best-corrected (BCVA) was 0.8 the right eye 0.05 left. On slit-lamp examination, inflammatory findings were observed anterior chamber body fundus vascular sheat...

Churg-Strauss angiitis or syndrome (CSA) is defined as an eosinophil-rich and granulomatous inflammation involving the respiratory tract, and necrotising vasculitis affecting small- to medium-sized vessels, and is associated with asthma and eosinophilia. It is usually classified among the so-called anti-neutrophil antibody (ANCA)-associated systemic vasculitides (AASVs) because of its clinical ...