نتایج جستجو برای: allergic airway inflammation

تعداد نتایج: 272736  

Journal: :International Journal of Molecular Sciences 2019

Journal: :Journal of Allergy and Clinical Immunology 2017

Journal: :International Archives of Allergy and Immunology 2006

Journal: :Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2008
S Tourdot S Mathie T Hussell L Edwards H Wang P J M Openshaw J Schwarze C M Lloyd

BACKGROUND The mechanisms underlying exacerbation of asthma induced by respiratory syncytial virus (RSV) infection have been extensively studied in human and animal models. However, most of these studies focused on acute inflammation and little is known of its long-term consequences on remodelling of the airway tissue. OBJECTIVE The aim of the study was to use a murine model of prolonged alle...

2016
Hadeesha Piyadasa Anthony Altieri Sujata Basu Jacquie Schwartz Andrew J. Halayko Neeloffer Mookherjee

House dust mite (HDM) challenge is commonly used in murine models of allergic asthma for preclinical pathophysiological studies. However, few studies define objective readouts or biomarkers in this model. In this study we characterized immune responses and defined molecular markers that are specifically altered after HDM challenge. In this murinemodel, we used repeated HDM challenge for twoweek...

2013
Li Zhou Sun Young Oh Yuqi Zhou Baojun Yuan Fan Wu Min Hee Oh Yefu Wang Cliff Takemoto Nico Van Rooijen Tao Zheng Zhou Zhu

Allergic inflammation and severe allergic reactions (anaphylaxis) are important in allergen induced diseases. Bacterial products such as lipopolysaccharide (LPS) are ubiquitous and can facilitate allergen induced Th2 immune responses. Phosphatase SHP-1 is critical in regulating immunological homeostasis and in allergen induced Th2 immune responses in the lung. However, the mechanisms underlying...

Journal: :Current Opinion in Allergy & Clinical Immunology 2010

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