The Pd-catalyzed intramolecular addition of carbamoyl chlorides and aryl halides across alkynes is investigated by means of DFT calculations and mechanistic test experiments. The data suggest a mechanistic pathway that involves oxidative addition, alkyne insertion, cis / trans isomerization and reductive elimination. Our data indicate that oxidative addition is the reactivity limiting step in t...

A previous study showed that ammonia oxidation by the Thaumarchaeota Nitrosopumilus maritimus (group 1.1a) was resistant to concentrations of the C8 1-alkyne, octyne, which completely inhibits activity by ammonia-oxidizing bacteria. In this study, the inhibitory effects of octyne and other C2 to C10 1-alkynes were evaluated on the nitrite production activity of two pure culture isolates from Th...

Presented are the results of a systematic investigation of the reactions of nine-atom deltahedral clusters of germanium (Zintl ions, Ge(9)(n-)) with alkynes and alkyl halides that result in alkenylation and alkylation of the clusters, respectively. The reaction pathways have been probed in depth using various, appropriately substituted alkynes and organic halides, including some typical mechani...

highly active cu (ii) complex with 1,4-dihydroxy anthraquinone as a cheap and accessable ligand could be used as a catalyst for the preparation of structurally different propargylamines from a one-pot, three-component reaction of terminal alkynes, aldehydes, and secondary amines with high yields under solvent-free conditions. the 1,4-dihydroxy anthraquinone is a very efficient cu(ii) scavenger ...

Stable and isolable alkanethiolate-stabilized Pt nanoparticles (PtNP) were synthesized using the two-phase thiosulfate method with sodium S-alkylthiosulfate as ligand precursor. The mechanistic formation of octanethiolate-capped PtNP (Pt-SC8) from both sodium S-octylthiosulfate and 1-octanethiol ligands was investigated by using 1H NMR and UV-vis spectroscopies, which revealed the formation of ...

Ethynylbenziodoxolones (EBXs) have recently emerged as potent reagents for the alkynylation of radicals. Their combination with photocatalysis allows synthesis valuable alkynes at room temperature. Herein, we discuss two photomediated strategies internal alkynes. The first transformation is a 1,2-oxyalkynylation N- and O-alkenes using 4ClCzIPN photocatalyst. second strategy makes use EBXs stron...

A ligand-promoted, palladium-catalyzed transfer hydrogenation of terminal alkynes using ethanol as the hydrogen donor is developed. The chemical selectivity control achieved based on ligand regulation. use triethanolamine and tetrahydrofuran at 80 °C under N 2 found to be critical for alkynes. general applicability this procedure highlighted by synthesis 27 alkenes in moderate good yields.

Greatness in simplicity: A general, straightforward, and atom-economical protocol to synthesize vinyl triflimides has been developed. broad spectrum of terminal internal alkynes could be used generate various di- trisubstituted triflimides. The conducted on a gram scale with both alkynes. Preliminarily attempts probe the unprecedented reactivity disclosed some its unique chemical properties. Mo...

The Ni-catalyzed reaction of aromatic amides with alkynes in the presence of KOBu t involves C-H/N-H oxidative annulation to give 1(2H)-isoquinolinones. A key to the success of the reaction is the use of a catalytic amount of strong base, such as KOBu t . The reaction shows a high functional group compatibility. The reaction with unsymmetrical alkynes, such as 1-arylalkynes, gives the correspon...